SPG11

Description		SPG11 vesicle trafficking associated, spatacsin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Cytosol Plasma Membrane Axon Dendrite Cytoplasmic Vesicle Cell Projection Synapse
	Molecular Function	Protein Binding Protein Kinase Binding
	Biological Process	Protein Import Into Nucleus Intracellular Protein Transport Lysosome Organization Chemical Synaptic Transmission Axonogenesis Neuromuscular Junction Development Memory Axo-dendritic Transport Intracellular Protein Localization Corticospinal Tract Morphogenesis Protein Catabolic Process Cholesterol Efflux Vesicle Transport Along Microtubule Synaptic Vesicle Transport Axon Extension Skeletal Muscle Fiber Development Neuron Apoptotic Process Localization Within Membrane Motor Behavior Phagosome-lysosome Fusion Involved In Apoptotic Cell Clearance Walking Behavior Motor Neuron Apoptotic Process Autophagosome Organization Regulation Of Store-operated Calcium Entry
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS		Anti-Toxoplasma gondii IgG seropositivity ( 30610941) Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)
Novel Interacting Genes		1 novel interacting genes: PAK6
Interacting Genes		1 interacting genes: SERTAD3
Entrez ID		80208
HPRD ID		07963
Ensembl ID		ENSG00000104133
Uniprot IDs		A0A804HID9 Q96JI7
PDB IDs
Enriched GO Terms of Interacting Partners?
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