TREML2

Description		triggering receptor expressed on myeloid cells like 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane
	Molecular Function	Protein Binding Signaling Receptor Activity
	Biological Process	T Cell Activation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 24162737) Blood protein levels ( 30072576) Monocyte count ( 27863252 32888494) Reticulocyte count ( 32888494) Type 2 diabetes ( 31049640) Waist circumference ( 28552196) White blood cell count ( 32888494)
Novel Interacting Genes		2 novel interacting genes: CSF2 HDAC2
Interacting Genes
Entrez ID		79865
HPRD ID		11646
Ensembl ID		ENSG00000112195
Uniprot IDs		Q5T2D2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Behavior Granulocyte Macrophage Colony-stimulating Factor Receptor Binding Positive Regulation Of Male Mating Behavior Response To Molecule Of Bacterial Origin Response To Lipopolysaccharide Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway Granulocyte Macrophage Colony-stimulating Factor Receptor Complex Response To Silicon Dioxide Protein Decrotonylase Activity Histone Decrotonylase Activity Protein De-2-hydroxyisobutyrylase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation Hair Follicle Placode Formation Positive Regulation Of Podosome Assembly Positive Regulation Of Cytokine Production Regulation Of Podosome Assembly Positive Regulation Of Interleukin-23 Production Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Epithelial Fluid Transport Regulation Of Interleukin-23 Production Neutrophil Differentiation Histamine Transport Cellular Response To Lipid Histamine Secretion Cellular Response To Dopamine Negative Regulation Of Transcription By Competitive Promoter Binding Eyelid Development In Camera-type Eye Behavioral Response To Ethanol Deacetylase Activity Protein Lysine Deacetylase Activity Progesterone Receptor Signaling Pathway Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Dopamine Histone Deacetylase Activity, Hydrolytic Mechanism Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Negative Regulation Of Dendritic Spine Development ESC/E(Z) Complex Response To Caffeine Regulation Of Cytokine Production Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Cell Population Proliferation Response To Lipid Negative Regulation Of Programmed Cell Death Embryonic Placenta Development Monocyte Differentiation Negative Regulation Of Apoptotic Process Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Circadian Sleep/wake Cycle Cellular Response To Oxygen-containing Compound
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