MYH14

Description		myosin heavy chain 14
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GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Brush Border Membrane Myosin Complex Myosin II Complex Axon Growth Cone Myosin Filament Actomyosin Extracellular Exosome Myosin II Filament Supramolecular Fiber
	Molecular Function	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Calmodulin Binding ATP Binding Actin Filament Binding
	Biological Process	Mitotic Cytokinesis Skeletal Muscle Contraction Mitochondrion Organization Skeletal Muscle Tissue Development Sensory Perception Of Sound Regulation Of Cell Shape Neuronal Action Potential Actin Filament-based Movement Actomyosin Structure Organization Vocalization Behavior
Pathways		EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs		(S)-blebbistatin Mant-Adp Tetrafluoroaluminate Ion (3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one (3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one (3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium(1-)
Diseases
GWAS		Disc degeneration (lumbar) ( 22993228) Glucose homeostasis traits ( 25524916)
Interacting Genes		6 interacting genes: FNDC3B GFI1B ITSN1 PDE4B RNF10 SNAPIN
Entrez ID		79784
HPRD ID		10543
Ensembl ID		ENSG00000105357
Uniprot IDs		A1L2Z2 B3KWH4 Q7Z406
PDB IDs		5I4E 5JLH
Enriched GO Terms of Interacting Partners?
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