FZD3

Gene Name		frizzled class receptor 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Apical Plasma Membrane Lateral Plasma Membrane Axon Dendrite Neuronal Cell Body Presynaptic Active Zone
	Molecular Function	G-protein Coupled Receptor Activity Protein Binding Wnt-protein Binding PDZ Domain Binding Wnt-activated Receptor Activity
	Biological Process	Establishment Of Planar Polarity Neuron Migration Neural Tube Closure Hair Follicle Development Positive Regulation Of Neuroblast Proliferation G-protein Coupled Receptor Signaling Pathway Neuron Differentiation Cell Proliferation In Midbrain Non-canonical Wnt Signaling Pathway Post-anal Tail Morphogenesis Inner Ear Morphogenesis Negative Regulation Of Mitotic Cell Cycle, Embryonic Canonical Wnt Signaling Pathway Sympathetic Ganglion Development Commissural Neuron Axon Guidance Negative Regulation Of Execution Phase Of Apoptosis
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Ca2+ pathway Asymmetric localization of PCP proteins Signaling by Wnt Metabolic disorders of biological oxidation enzymes GPCR ligand binding PCP/CE pathway Class B/2 (Secretin family receptors) beta-catenin independent WNT signaling
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: GIPC1 GIPC2 GIPC3
Entrez ID		7976
HPRD ID		05849
Ensembl ID		ENSG00000104290
Uniprot IDs		A8K615 Q9NPG1
PDB IDs
Enriched GO Terms of Interacting Partners?		Glutamate Secretion Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cytokinesis Acid Secretion Regulation Of Cytokinesis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Endothelial Cell Migration Dicarboxylic Acid Transport Epithelial Cell Migration Epithelium Migration Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Protein Catabolic Process Positive Regulation Of Cell Division Regulation Of Protein Stability Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?		adds arealization axon axons barrel celsr2 celsr3 conditional contexts forebrain guidance guidepost inactivation mimics navigation pcp perturbs planar polarity projections redundantly thalamic thalamocortical thalamus unexpectedly vangl vangl1 vangl2 wiring