ZNF750

Description		zinc finger protein 750
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GO Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Metal Ion Binding Promoter-specific Chromatin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Epidermis Development Positive Regulation Of Gene Expression Negative Regulation Of Epithelial To Mesenchymal Transition Cell Differentiation Membrane Biogenesis Positive Regulation Of Transcription By RNA Polymerase II Establishment Of Skin Barrier Positive Regulation Of Ceramide Biosynthetic Process
Pathways		Generic Transcription Pathway
Drugs
Diseases		Seborrhea-like dermatitis with psoriasiform element
GWAS		Response to cognitive-behavioural therapy in anxiety and major depressive disorders ( 31123309)
Interacting Genes		5 interacting genes: CTBP1 CTBP2 KDM1A KLF4 RCOR1
Entrez ID		79755
HPRD ID		08588
Ensembl ID		ENSG00000141579
Uniprot IDs		Q32MQ0
PDB IDs		8SXM
Enriched GO Terms of Interacting Partners?		Transcription Corepressor Activity Transcription Coregulator Binding Transcription Repressor Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Fat Cell Differentiation Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA Repair Complex White Fat Cell Differentiation DNA-binding Transcription Factor Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Viral Genome Replication LncRNA Binding Transcription Regulator Complex Histone Methyltransferase Complex Negative Regulation Of Macromolecule Biosynthetic Process NAD Binding Negative Regulation Of Biosynthetic Process Transcription Coactivator Activity Negative Regulation Of Transcription By RNA Polymerase II Cell Differentiation Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Transcription Corepressor Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Negative Regulation Of Metabolic Process Cellular Developmental Process Promoter-specific Chromatin Binding Regulation Of DNA-templated Transcription Chromatin Binding Regulation Of RNA Biosynthetic Process Oxidoreductase Activity RNA Polymerase II Sequence-specific DNA-binding Transcription Factor Recruiting Activity Negative Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Regulation Of Cell Population Proliferation Positive Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of Muscle Hyperplasia Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Cell Population Proliferation Viral Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Blastocyst Development Mesodermal Cell Fate Determination Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling
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