PPP1R3B

Gene Name		protein phosphatase 1, regulatory subunit 3B
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Gene Ontology Annotations	Cellular Component	Protein Phosphatase Type 1 Complex Glycogen Granule Intracellular Membrane-bounded Organelle
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Phosphatase Regulator Activity Enzyme Binding
	Biological Process	Glycogen Metabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Glycogen Catabolic Process Dephosphorylation Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease ( 22832961) C-reactive protein ( 21300955) Cholesterol, total ( 20686565) Coronary heart disease ( 21347282) Fasting glucose-related traits (interaction with BMI) ( 22581228) Fasting insulin-related traits (interaction with BMI) ( 22581228) HDL cholesterol ( 23726366 23505323 20686565) LDL cholesterol ( 20864672 20686565) Liver enzyme levels (alkaline phosphatase) ( 22001757) Metabolite levels ( 22916037) Myopia (pathological) ( 23049088)
Protein-protein Interactions		2 interactors: IFNAR2 PPP1CA
Entrez ID		79660
HPRD ID		17894
Ensembl ID		ENSG00000173281
Uniprot IDs		Q86XI6
PDB IDs		2EEF
Enriched GO Terms of Interacting Partners?		Regulation Of Glycogen Catabolic Process Response To Interferon-alpha Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Glycogen Metabolic Process Regulation Of Type I Interferon-mediated Signaling Pathway JAK-STAT Cascade Glycogen Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To External Stimulus Regulation Of Generation Of Precursor Metabolites And Energy Cellular Response To Organic Substance Circadian Regulation Of Gene Expression Polysaccharide Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Triglyceride Metabolic Process Regulation Of Circadian Rhythm Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Glucose Metabolic Process Neutral Lipid Metabolic Process Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Response To Type I Interferon Response To Organic Substance Energy Reserve Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Lipid Catabolic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Signal Transduction Circadian Rhythm Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Branching Morphogenesis Of An Epithelial Tube Regulation Of Signaling Cell Surface Receptor Signaling Pathway Cellular Carbohydrate Metabolic Process Morphogenesis Of A Branching Epithelium Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Tagcloud ?		05e abca7 apoe attributable bin1 cd2ap cd33 clu cr1 epha1 gwas gwass illumina imputed loci meta ms4a4 ms4a6e nominal omni1 picalm pittsburg pittsburgh quad rs3848140 snp snps suggestive top