PAGR1

Description		PAXIP1 associated glutamate rich protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Histone Methyltransferase Complex MLL3/4 Complex
	Molecular Function	Protein Binding Nuclear Estrogen Receptor Binding
	Biological Process	DNA Repair DNA Recombination DNA Damage Response Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Cycle G1/S Phase Transition
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis Formation of WDR5-containing histone-modifying complexes Epigenetic regulation of gene expression by MLL3 and MLL4 complexes MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: DCTPP1
Interacting Genes		4 interacting genes: APP ESR1 NCOA1 PAXIP1
Entrez ID		79447
HPRD ID		14647
Ensembl ID		ENSG00000280789
Uniprot IDs		Q9BTK6
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin Remodeling Negative Regulation Of MiRNA Transcription Chromatin Organization Mating Behavior Estrogen Receptor Signaling Pathway Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Toll-like Receptor Signaling Pathway Reproductive Behavior Nuclear Estrogen Receptor Binding Positive Regulation Of Nitric Oxide Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Response To Calcium Ion Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Neuron Differentiation Chromatin Binding Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-binding Transcription Factor Activity Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose DTTP Catabolic Process DCTP Diphosphatase Activity DCTP Catabolic Process Nuclear Receptor-mediated Signaling Pathway Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Response To Estradiol Male Gonad Development Acetylcholine Receptor Activator Activity Intracellular Signal Transduction Positive Regulation Of RNA Metabolic Process Lipoprotein Particle Positive Regulation Of Protein Import Labyrinthine Layer Morphogenesis Pyrimidine Deoxyribonucleotide Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
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