DHRS11

Description		dehydrogenase/reductase 11
Image
GO Annotations	Cellular Component	Extracellular Region
	Molecular Function	Nucleotide Binding 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) Activity Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor 17-beta-hydroxysteroid Dehydrogenase (NADP+) Activity
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Estrogen Biosynthetic Process Steroid Metabolic Process
Pathways
Drugs		Nicotinamide adenine dinucleotide phosphate
Diseases
GWAS		Body mass index ( 26426971) Estimated glomerular filtration rate ( 31015462)
Novel Interacting Genes		1 novel interacting genes: GSDMB
Interacting Genes		1 interacting genes: DLG3
Entrez ID		79154
HPRD ID		08331
Ensembl ID		ENSG00000278535
Uniprot IDs		Q6UWP2
PDB IDs		1XG5
Enriched GO Terms of Interacting Partners?		Cytotoxic T Cell Pyroptotic Cell Death Phosphatase Binding Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Of Planar Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Ionotropic Glutamate Receptor Binding Receptor Clustering Receptor Localization To Synapse AMPA Glutamate Receptor Complex Biological Process Involved In Interaction With Symbiont Phosphatidylinositol-4-phosphate Binding Pyroptotic Inflammatory Response Pyroptotic Cell Death Wide Pore Channel Activity Killing By Host Of Symbiont Cells Granzyme-mediated Programmed Cell Death Signaling Pathway Cardiolipin Binding Protein Localization To Synapse Phosphatidylserine Binding Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Phosphatidylinositol-4,5-bisphosphate Binding Neuromuscular Junction Protein Localization To Cell Junction Defense Response To Gram-negative Bacterium Postsynaptic Density Membrane Kinase Binding Bicellular Tight Junction Killing Of Cells Of Another Organism Phospholipid Binding
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