ERI3

Description		ERI1 exoribonuclease family member 3
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GO Annotations	Cellular Component
	Molecular Function	3'-5'-RNA Exonuclease Activity Nucleic Acid Binding RNA Binding Nuclease Activity Exonuclease Activity Hydrolase Activity Metal Ion Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Anxiety ( 33859377) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
Novel Interacting Genes		1 novel interacting genes: HOOK1
Interacting Genes		6 interacting genes: CENPO CPEB2 FNDC3B PRNP SHANK3 YTHDF1
Entrez ID		79033
HPRD ID		15175
Ensembl ID		ENSG00000117419
Uniprot IDs		B4DEX5 B4DN03 O43414
PDB IDs		2XRI 7K05 7K06 7K07 7LPY 7LPZ 7LQ0
Enriched GO Terms of Interacting Partners?		Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Glutamate Receptor Signaling Pathway Regulation Of Glutamate Receptor Signaling Pathway Memory Regulation Of Synaptic Plasticity Dendritic Spine Organization Learning Or Memory Neuron Projection Organization Postsynapse Organization Cognition Type 8 Metabotropic Glutamate Receptor Binding Ribosome Binding Mis6-Sim4 Complex Negative Regulation Of Cytoplasmic Translational Elongation Modulation Of Chemical Synaptic Transmission Guanylate Kinase-associated Protein Clustering Cellular Component Assembly Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Postsynapse Organization Negative Regulation Of Dendritic Spine Maintenance Cupric Ion Binding Regulation Of Cell Projection Organization Type 5 Metabotropic Glutamate Receptor Binding FHF Complex Learning Centromere Complex Assembly Negative Regulation Of Cell Volume AMPA Glutamate Receptor Clustering Synaptic Receptor Adaptor Activity Positive Regulation Of Synapse Structural Plasticity NMDA Glutamate Receptor Clustering Striatal Medium Spiny Neuron Differentiation Negative Regulation Of Translational Elongation ATP-dependent Protein Binding Aspartic-type Endopeptidase Inhibitor Activity Manchette Assembly Postsynaptic Density Assembly Regulation Of Synapse Structural Plasticity Protein Localization To Perinuclear Region Of Cytoplasm Vocal Learning Neuron Spine Cuprous Ion Binding Positive Regulation Of Long-term Neuronal Synaptic Plasticity Observational Learning Negative Regulation Of Cytoplasmic Translation Postsynaptic Density Microtubule Binding Dendritic Spine Maintenance Nervous System Process Postsynaptic Specialization Assembly
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