ERI3

Gene Name		ERI1 exoribonuclease family member 3
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Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm
	Molecular Function	3'-5'-exoribonuclease Activity Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: CENPO PRNP
Entrez ID		79033
HPRD ID		15175
Ensembl ID		ENSG00000117419
Uniprot IDs		B4DEX5 B4DN03 O43414
PDB IDs		2XRI
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Copper Ion Negative Regulation Of Calcium-mediated Signaling Negative Regulation Of Interleukin-17 Production Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Activated T Cell Proliferation Negative Regulation Of Interleukin-2 Production Cellular Copper Ion Homeostasis Negative Regulation Of T Cell Receptor Signaling Pathway Response To Copper Ion Copper Ion Homeostasis Protein Complex Assembly CENP-A Containing Nucleosome Assembly Histone Exchange Negative Regulation Of Interferon-gamma Production DNA Replication-independent Nucleosome Assembly Regulation Of Activated T Cell Proliferation Regulation Of Potassium Ion Transmembrane Transport Cell Cycle Regulation Of Calcium-mediated Signaling Regulation Of T Cell Receptor Signaling Pathway Centromere Complex Assembly Response To Cadmium Ion Regulation Of Potassium Ion Transport Negative Regulation Of T Cell Proliferation ATP-dependent Chromatin Remodeling Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Leukocyte Proliferation Cellular Component Assembly Regulation Of Interferon-gamma Production Negative Regulation Of T Cell Activation Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleosome Assembly Cellular Response To Metal Ion Negative Regulation Of Lymphocyte Activation Negative Regulation Of Cell-cell Adhesion Chromatin Assembly Cellular Response To Inorganic Substance Nucleosome Organization Regulation Of T Cell Proliferation Cell Cycle Arrest Transition Metal Ion Homeostasis Chromatin Assembly Or Disassembly Negative Regulation Of Leukocyte Activation Protein-DNA Complex Assembly Chromatin Remodeling DNA Packaging
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