ALMS1

Description		ALMS1 centrosome and basal body associated protein
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Mitochondrion Centrosome Centriole Cytosol Cytoskeleton Cilium Microtubule Cytoskeleton Ciliary Basal Body Cell Projection
	Molecular Function	Protein Binding
	Biological Process	Endosomal Transport Regulation Of Centriole Replication Regulation Of Stress Fiber Assembly Positive Regulation Of Cold-induced Thermogenesis
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases		Alstrom syndrome (AS)
GWAS		Age at voice drop ( 27182965) Blood metabolite levels ( 26401656) Chronic kidney disease ( 20383146) Creatinine levels ( 20383145) Estimated glomerular filtration rate ( 31451708 31015462) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 27588450) Glomerular filtration rate (creatinine) ( 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) High density lipoprotein cholesterol levels ( 33339817) Intelligence (MTAG) ( 29326435) Menarche (age at onset) ( 27182965) Metabolite levels ( 21931564) Metabolite levels (X-11787) ( 23934736) Retinitis pigmentosa ( 33514863) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 23093944 33031748) Urinary metabolite levels in chronic kidney disease ( 29545352) Urinary metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolites (H-NMR features) ( 24586186)
Novel Interacting Genes		4 novel interacting genes: CNOT7 ELN HRH4 SLC4A5
Interacting Genes		3 interacting genes: GTF2IRD1 LIG4 MEGF10
Entrez ID		7840
HPRD ID		06023
Ensembl ID		ENSG00000116127
Uniprot IDs		Q8TCU4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?