ZNF224

Description		zinc finger protein 224
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Repressor Complex Nuclear Membrane
	Molecular Function	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways		Generic Transcription Pathway Regulation of endogenous retroelements by KRAB-ZFP proteins Regulation of endogenous retroelements by KRAB-ZFP proteins
Drugs
Diseases
GWAS		Alzheimer's disease ( 19118814)
Interacting Genes		5 interacting genes: APP CLIC6 MAGEA8 MTUS2 PRMT5
Entrez ID		7767
HPRD ID		06094
Ensembl ID		ENSG00000267680
Uniprot IDs		Q9NZL3
PDB IDs		2ELY 2ELZ 2EM0 2EM6 2EM7 2EM8 2EM9 2EN1 2EN8 2ENA 2ENC 2EOQ 2EOR 2EQ4 2YSP 2YTH
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Regulation Of G Protein-coupled Receptor Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Peptidyl-arginine N-methylation Histone Arginine N-methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity D2 Dopamine Receptor Binding D4 Dopamine Receptor Binding D3 Dopamine Receptor Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Histone H4R3 Methyltransferase Activity Positive Regulation Of Dopamine Receptor Signaling Pathway Peptidyl-arginine Methylation Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Epigenetic Regulation Of Gene Expression Regulation Of ERK1 And ERK2 Cascade Cellular Response To Manganese Ion
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