C9

Gene Name		complement component 9
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Membrane Attack Complex Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function
	Biological Process	Complement Activation, Alternative Pathway Complement Activation, Classical Pathway Hemolysis By Symbiont Of Host Erythrocytes Regulation Of Complement Activation Innate Immune Response
Pathways		Regulation of Complement cascade Complement cascade Terminal pathway of complement Innate Immune System
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146)
Protein-protein Interactions		3 interactors: C8A CD59 CLU
Entrez ID		735
HPRD ID		00408
Ensembl ID		ENSG00000113600
Uniprot IDs		P02748
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Complement Activation Regulation Of Humoral Immune Response Regulation Of Acute Inflammatory Response Innate Immune Response Regulation Of Immune Response Positive Regulation Of Immune System Process Complement Activation, Classical Pathway Humoral Immune Response Mediated By Circulating Immunoglobulin Complement Activation Positive Regulation Of Tau-protein Kinase Activity Microglial Cell Proliferation Regulation Of Neuronal Signal Transduction Negative Regulation Of Activation Of Membrane Attack Complex Protein Activation Cascade Immune Response Regulation Of Immune System Process Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Defense Response Positive Regulation Of Neurofibrillary Tangle Assembly Humoral Immune Response Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Leukocyte Mediated Immunity Adaptive Immune Response Regulation Of Inflammatory Response Central Nervous System Myelin Maintenance Regulation Of Tau-protein Kinase Activity Negative Regulation Of Protein Homooligomerization Immune System Process Positive Regulation Of Inclusion Body Assembly Regulation Of Beta-amyloid Clearance Regulation Of Protein Metabolic Process Regulation Of Protein Processing Blood Coagulation Hemostasis Positive Regulation Of Beta-amyloid Formation Negative Regulation Of Protein Oligomerization Negative Regulation Of Beta-amyloid Formation Complement Activation, Alternative Pathway Chaperone-mediated Protein Complex Assembly Microglial Cell Activation Negative Regulation Of Complement Activation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Body Fluid Levels Glial Cell Proliferation Wound Healing Response To Misfolded Protein Regulation Of Beta-amyloid Formation Positive Regulation Of Immune Response Regulation Of Inclusion Body Assembly
Tagcloud ?		astroglial axotomy bromodeoxyuridine c3d complement degeneration degenerative enables gfap glial hypoglossal immunoreactivity injured ipsilateral massive microglial motorneuron nerve oligodendroglial ox42 phagocytosis principally profound rca ricin situation somata transection transferrin