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UBA7
Gene Name
ubiquitin-like modifier activating enzyme 7
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Molecular Function
Ubiquitin Activating Enzyme Activity
Ubiquitin-protein Transferase Activity
ATP Binding
ISG15 Activating Enzyme Activity
Biological Process
Cellular Protein Modification Process
Protein Ubiquitination
Cytokine-mediated Signaling Pathway
Modification-dependent Protein Catabolic Process
ISG15-protein Conjugation
Negative Regulation Of Type I Interferon Production
Innate Immune Response
Pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Antigen processing: Ubiquitination & Proteasome degradation
Negative regulators of RIG-I/MDA5 signaling
ISG15 antiviral mechanism
Interferon Signaling
Cytokine Signaling in Immune system
Class I MHC mediated antigen processing & presentation
Antiviral mechanism by IFN-stimulated genes
Adaptive Immune System
Innate Immune System
Drugs
Diseases
GWAS
Ulcerative colitis (
21297633
)
Protein-protein Interactions
4 interactors:
FAS
ISG15
UBE2L3
UBE2L6
Entrez ID
7318
HPRD ID
01873
Ensembl ID
ENSG00000182179
Uniprot IDs
P41226
PDB IDs
Enriched GO Terms of Interacting Partners
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ISG15-protein Conjugation
Negative Regulation Of Type I Interferon Production
Modification-dependent Protein Catabolic Process
Cellular Response To Organic Substance
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Response To Cytokine Stimulus
Protein Catabolic Process
Response To Cytokine
Regulation Of Type I Interferon Production
Response To Organic Substance
Cellular Macromolecule Catabolic Process
Response To Glucocorticoid
Response To Corticosteroid
Motor Neuron Apoptotic Process
Regulation Of Myeloid Cell Differentiation
Regulation Of Protein Ubiquitination
Negative Regulation Of Cytokine Production
Immune Response
Necroptotic Signaling Pathway
Proteolysis
Transformed Cell Apoptotic Process
Activation-induced Cell Death Of T Cells
Inflammatory Cell Apoptotic Process
Cellular Response To Hyperoxia
Positive Regulation Of Protein Homooligomerization
Catabolic Process
Pantothenate Metabolic Process
Cytokine-mediated Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Response To Steroid Hormone
Negative Thymic T Cell Selection
Negative T Cell Selection
Long-chain Fatty-acyl-CoA Biosynthetic Process
Immune System Process
Cellular Response To Lithium Ion
T Cell Apoptotic Process
Regulation Of Protein Metabolic Process
Regulation Of Cytokine Production
Protein Metabolic Process
Fatty-acyl-CoA Biosynthetic Process
Positive Regulation Of Protein Oligomerization
Hepatocyte Apoptotic Process
Protein Ubiquitination
Positive Regulation Of Erythrocyte Differentiation
Protein K11-linked Ubiquitination
Thymic T Cell Selection
Acetyl-CoA Metabolic Process
Long-chain Fatty-acyl-CoA Metabolic Process
Protein Modification By Small Protein Conjugation
Tagcloud
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