UBA7

Gene Name		ubiquitin-like modifier activating enzyme 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol
	Molecular Function	Ubiquitin Activating Enzyme Activity Ubiquitin-protein Transferase Activity ATP Binding ISG15 Activating Enzyme Activity
	Biological Process	Cellular Protein Modification Process Protein Ubiquitination Cytokine-mediated Signaling Pathway Modification-dependent Protein Catabolic Process ISG15-protein Conjugation Negative Regulation Of Type I Interferon Production Innate Immune Response
Pathways		RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Antigen processing: Ubiquitination & Proteasome degradation Negative regulators of RIG-I/MDA5 signaling ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Class I MHC mediated antigen processing & presentation Antiviral mechanism by IFN-stimulated genes Adaptive Immune System Innate Immune System
Drugs
Diseases
GWAS		Ulcerative colitis ( 21297633)
Protein-protein Interactions		4 interactors: FAS ISG15 UBE2L3 UBE2L6
Entrez ID		7318
HPRD ID		01873
Ensembl ID		ENSG00000182179
Uniprot IDs		P41226
PDB IDs
Enriched GO Terms of Interacting Partners?		ISG15-protein Conjugation Negative Regulation Of Type I Interferon Production Modification-dependent Protein Catabolic Process Cellular Response To Organic Substance Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Response To Cytokine Stimulus Protein Catabolic Process Response To Cytokine Regulation Of Type I Interferon Production Response To Organic Substance Cellular Macromolecule Catabolic Process Response To Glucocorticoid Response To Corticosteroid Motor Neuron Apoptotic Process Regulation Of Myeloid Cell Differentiation Regulation Of Protein Ubiquitination Negative Regulation Of Cytokine Production Immune Response Necroptotic Signaling Pathway Proteolysis Transformed Cell Apoptotic Process Activation-induced Cell Death Of T Cells Inflammatory Cell Apoptotic Process Cellular Response To Hyperoxia Positive Regulation Of Protein Homooligomerization Catabolic Process Pantothenate Metabolic Process Cytokine-mediated Signaling Pathway Regulation Of Cellular Protein Metabolic Process Response To Steroid Hormone Negative Thymic T Cell Selection Negative T Cell Selection Long-chain Fatty-acyl-CoA Biosynthetic Process Immune System Process Cellular Response To Lithium Ion T Cell Apoptotic Process Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Protein Metabolic Process Fatty-acyl-CoA Biosynthetic Process Positive Regulation Of Protein Oligomerization Hepatocyte Apoptotic Process Protein Ubiquitination Positive Regulation Of Erythrocyte Differentiation Protein K11-linked Ubiquitination Thymic T Cell Selection Acetyl-CoA Metabolic Process Long-chain Fatty-acyl-CoA Metabolic Process Protein Modification By Small Protein Conjugation
Tagcloud ?