C7

Gene Name		complement component 7
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Membrane Attack Complex Extracellular Vesicular Exosome
	Molecular Function
	Biological Process	Cellular Sodium Ion Homeostasis Complement Activation Complement Activation, Alternative Pathway Complement Activation, Classical Pathway Cytolysis Regulation Of Complement Activation Innate Immune Response
Pathways		Regulation of Complement cascade Complement cascade Terminal pathway of complement Innate Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: C5 CLU PLG
Entrez ID		730
HPRD ID		01957
Ensembl ID		ENSG00000112936
Uniprot IDs		P10643 Q05CI3
PDB IDs		2WCY
Enriched GO Terms of Interacting Partners?		Platelet Degranulation Complement Activation, Classical Pathway Humoral Immune Response Mediated By Circulating Immunoglobulin Complement Activation Positive Regulation Of Tau-protein Kinase Activity Microglial Cell Proliferation Regulation Of Neuronal Signal Transduction Protein Activation Cascade Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Platelet Activation Negative Regulation Of Macrophage Chemotaxis Positive Regulation Of Neurofibrillary Tangle Assembly Leukocyte Migration Humoral Immune Response Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Mononuclear Cell Migration Leukocyte Mediated Immunity Adaptive Immune Response Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Central Nervous System Myelin Maintenance Positive Regulation Of Fibrinolysis Regulation Of Tau-protein Kinase Activity Negative Regulation Of Dopamine Secretion Exocytosis Negative Regulation Of Protein Homooligomerization Positive Regulation Of Cytokine Production Immune System Process Positive Regulation Of Inclusion Body Assembly Regulation Of Beta-amyloid Clearance Negative Regulation Of Leukocyte Chemotaxis Negative Regulation Of Norepinephrine Secretion Blood Coagulation Hemostasis Positive Regulation Of Beta-amyloid Formation Negative Regulation Of Protein Oligomerization Positive Regulation Of Protein Kinase Activity Positive Regulation Of Chemokine Secretion Negative Regulation Of Beta-amyloid Formation Negative Regulation Of Fibrinolysis Positive Regulation Of Kinase Activity Secretion By Cell In Utero Embryonic Development Complement Activation, Alternative Pathway Regulation Of Cytokine Production Regulation Of Norepinephrine Secretion Chaperone-mediated Protein Complex Assembly Microglial Cell Activation Regulation Of Fibrinolysis Positive Regulation Of Transferase Activity
Tagcloud ?		111in 5f10 accumulation alpha4 antihuman coadministration cytokine dm eosinophil eosinophils greatly hp2 igg inducer integrin integrins intradermal intravenous maximal moab mol numerous paf slowly tnfalpha tnfr totally uk vcam