TYR

Gene Name		tyrosinase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosome Golgi-associated Vesicle Integral Component Of Membrane Melanosome Membrane Melanosome Perinuclear Region Of Cytoplasm
	Molecular Function	Monophenol Monooxygenase Activity Copper Ion Binding Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Melanin Biosynthetic Process From Tyrosine Eye Pigment Biosynthetic Process Visual Perception Cell Proliferation Thymus Development Oxidation-reduction Process
Pathways
Drugs		NADH Azelaic Acid Monobenzone Mimosine
Diseases
GWAS		Age-related macular degeneration ( 23326517) Blue vs. green eyes ( 17952075) Eye color ( 20585627) Freckles ( 17952075) Melanoma ( 21983787 19578364) Skin pigmentation ( 17999355) Skin sensitivity to sun ( 17952075) Sunburns ( 23548203) Tanning ( 23548203 19340012) Vitiligo ( 20410501 22561518)
Protein-protein Interactions		1 interactors: TYRP1
Entrez ID		7299
HPRD ID		06086
Ensembl ID		ENSG00000077498
Uniprot IDs		L8B082 P14679
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetoacetic Acid Metabolic Process Short-chain Fatty Acid Metabolic Process Melanin Biosynthetic Process Melanin Metabolic Process Melanosome Organization Secondary Metabolite Biosynthetic Process Pigment Granule Organization Melanocyte Differentiation Neuroepithelial Cell Differentiation Pigment Biosynthetic Process Cellular Pigmentation Developmental Pigmentation Phenol-containing Compound Metabolic Process Pigmentation Vesicle Organization Fatty Acid Metabolic Process Epithelial Cell Differentiation Monocarboxylic Acid Metabolic Process
Tagcloud ?		5b carcinogens coactivator competition cooh cos delta12 deoxy genotoxic gh hormonal indirect j2 janus pd98059 peroxisome ppar pparalpha prolactin proliferator prostaglandin reconstituted stat1 stat5b structurally supershift talk transcriptionally transducer