TYMS

Gene Name		thymidylate synthetase
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol
	Molecular Function	Nucleotide Binding MRNA Binding Thymidylate Synthase Activity Folic Acid Binding Drug Binding Protein Homodimerization Activity Cofactor Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Metabolic Process DTMP Biosynthetic Process DTTP Biosynthetic Process Aging Circadian Rhythm Deoxyribonucleoside Monophosphate Biosynthetic Process Response To Toxic Substance Immortalization Of Host Cell By Virus Uracil Metabolic Process Organ Regeneration Methylation Response To Progesterone Response To Vitamin A Response To Cytokine Response To Drug Small Molecule Metabolic Process Response To Ethanol DUMP Metabolic Process Pyrimidine Nucleoside Biosynthetic Process Tetrahydrofolate Metabolic Process Response To Organophosphorus Developmental Growth Cartilage Development Response To Glucocorticoid Response To Folic Acid Nucleobase-containing Small Molecule Metabolic Process Intestinal Epithelial Cell Maturation
Pathways		E2F mediated regulation of DNA replication Pyrimidine biosynthesis G1/S Transition G1/S-Specific Transcription Pyrimidine metabolism Metabolism of nucleotides Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs		Raltitrexed Floxuridine Trifluridine Trimethoprim Gemcitabine Fluorouracil Pemetrexed Leucovorin Capecitabine Thymidine-5\'-Phosphate 10-Propargyl-5,8-Dideazafolic Acid 2\'-deoxyuridylic acid S,S-(2-Hydroxyethyl)Thiocysteine Pralatrexate 6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE
Diseases
GWAS
Protein-protein Interactions		2 interactors: SH3GL2 UPF2
Entrez ID		7298
HPRD ID		01774
Ensembl ID		ENSG00000176890
Uniprot IDs		P04818 Q53Y97
PDB IDs		1HVY 1HW3 1HW4 1HZW 1I00 1JU6 1JUJ 1YPV 2ONB 2RD8 2RDA 3EAW 3EBU 3ED7 3EDW 3EF9 3EGY 3EHI 3EJL 3GG5 3GH0 3GH2 3H9K 3HB8 3N5E 3N5G 3OB7 4E28 4FGT 4G2O 4G6W 4GD7 4GYH 4H1I
Enriched GO Terms of Interacting Partners?
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