TNP2

Name	transition protein 2
Structure	No pdb structure
Interactors	17 interactors: APPBP2 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 MDFI NOTCH2NLA PRKACA PRKACB PRKACG PRKCA
GO Annotations	Cellular Component	Nucleosome Nucleus Chromosome Nucleolus
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Spermatogenesis Acrosome Reaction Penetration Of Zona Pellucida Positive Regulation Of Protein Processing Cell Differentiation Sperm DNA Condensation
GWAS	Asthma ( 31959851 ) Bulimia nervosa ( 23568457 ) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007 ) Crohn's disease ( 28067908 ) Inflammatory bowel disease ( 28067908 ) Multiple sclerosis ( 22190364 ) Type 1 diabetes ( 18978792 )
Entrez ID	7142
HPRD ID	01831
Ensembl ID	ENSG00000178279
Uniprot IDs	Q05952 Q4VB56
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Keratin Filament Intermediate Filament CAMP-dependent Protein Kinase Activity CAMP-dependent Protein Kinase Complex High-density Lipoprotein Particle Assembly Vascular Endothelial Cell Response To Laminar Fluid Shear Stress Vascular Endothelial Cell Response To Fluid Shear Stress Cellular Response To Laminar Fluid Shear Stress Renal Water Homeostasis Response To Laminar Fluid Shear Stress Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Multicellular Organismal-level Water Homeostasis Cellular Response To Fluid Shear Stress Renal System Process Ciliary Base Response To Fluid Shear Stress Cytosol Multicellular Organismal-level Chemical Homeostasis Protein Kinase A Regulatory Subunit Binding Protein Serine Kinase Activity Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Protein Serine/threonine Kinase Activity Negative Regulation Of Smoothened Signaling Pathway Protein Kinase Activity Regulation Of Protein Processing Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Regulation Of Protein Maturation Negative Regulation Of TORC1 Signaling TORC1 Signaling Positive Regulation Of Dense Core Granule Biogenesis Histone H3T6 Kinase Activity Regulation Of Body Fluid Levels Kinase Activity Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Angiotensin-activated Signaling Pathway Alphav-beta3 Integrin-PKCalpha Complex Regulation Of Smoothened Signaling Pathway TOR Signaling Positive Regulation Of Insulin Secretion Neural Tube Closure