GPR137B

Description		G protein-coupled receptor 137B
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Plasma Membrane Membrane
	Molecular Function	Protein Binding
	Biological Process	Autophagy Regulation Of Autophagy Regulation Of Macrophage Activation Regulation Of GTPase Activity Negative Regulation Of Osteoclast Differentiation Negative Regulation Of Bone Resorption Positive Regulation Of Protein Localization To Lysosome Positive Regulation Of TORC1 Signaling
Pathways
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Metabolite levels ( 23823483) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309) Systolic blood pressure ( 27841878) Waist circumference adjusted for body mass index ( 28552196)
Novel Interacting Genes		2 novel interacting genes: AFF3 NLGN4X
Interacting Genes		2 interacting genes: APP TRIM32
Entrez ID		7107
HPRD ID		06878
Ensembl ID		ENSG00000077585
Uniprot IDs		O60478
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Chemokine Production Regulation Of Chemokine Production Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Neuron Differentiation Response To Peptide Response To Cytokine Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Interleukin-17-mediated Signaling Pathway Actin Ubiquitination Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production Regulation Of Nervous System Process Response To Tumor Necrosis Factor Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of Synapse Assembly Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Catabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Neuron Differentiation Endosome To Plasma Membrane Transport Vesicle Adult Behavior Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Learning Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Protein Localization To Phagocytic Vesicle Actin Modification Striated Muscle Myosin Thick Filament Asymmetric, Glutamatergic, Excitatory Synapse Symmetric, GABA-ergic, Inhibitory Synapse Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon
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