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TLL1
Gene Name
tolloid-like 1
Image
Gene Ontology Annotations
Cellular Component
Extracellular Region
Molecular Function
Metalloendopeptidase Activity
Calcium Ion Binding
Collagen Binding
Zinc Ion Binding
Biological Process
Skeletal System Development
Proteolysis
Extracellular Matrix Disassembly
Cell Differentiation
Extracellular Matrix Organization
Pathways
Collagen formation
Crosslinking of collagen fibrils
Anchoring fibril formation
Collagen biosynthesis and modifying enzymes
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS
Multiple sclerosis (
23412934
)
Obesity-related traits (
23251661
)
Post-traumatic stress disorder (
23726511
)
Post-traumatic stress disorder (asjusted for relatedness) (
23726511
)
Protein-protein Interactions
2 interactors:
APP
CHRD
Entrez ID
7092
HPRD ID
07074
Ensembl ID
ENSG00000038295
Uniprot IDs
B7ZLW3
E9PD25
O43897
PDB IDs
3EDI
Enriched GO Terms of Interacting Partners
?
BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning
Synaptic Growth At Neuromuscular Junction
Collateral Sprouting In Absence Of Injury
Forebrain Development
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning
Axon Choice Point Recognition
Floor Plate Development
Neuron Remodeling
Negative Regulation Of Cell Differentiation
Brain Development
Head Development
Cellular Copper Ion Homeostasis
Central Nervous System Development
Copper Ion Homeostasis
Suckling Behavior
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Neuron Maturation
MRNA Polyadenylation
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Spinal Cord Dorsal/ventral Patterning
Negative Regulation Of Smoothened Signaling Pathway
Spinal Cord Patterning
Mating Behavior
Endoplasmic Reticulum Calcium Ion Homeostasis
RNA Polyadenylation
Neuron Recognition
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Positive Regulation Of Mesenchymal Cell Proliferation
Negative Regulation Of BMP Signaling Pathway
Ionotropic Glutamate Receptor Signaling Pathway
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Negative Regulation Of Osteoblast Differentiation
Regulation Of Mesenchymal Cell Proliferation
Axon Cargo Transport
Mating
Neuromuscular Junction Development
Regulation Of Cell Differentiation
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Gastrulation With Mouth Forming Second
Neuron Apoptotic Process
Positive Regulation Of Cell Cycle Phase Transition
Regulation Of Protein Tyrosine Kinase Activity
Visual Learning
Glutamate Receptor Signaling Pathway
Visual Behavior
Neuron Death
Tagcloud
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abcc8
acacb
cacna1a
camk2d
cdkal1
chi
csmd1
disequilibrium
exome
glud1
gnas
hnf1a
hyperinsulinism
kcnh6
kcnj10
kcnj11
nos2
notch2
pde4c
pik3r3
probands
ryr3
scn8a
slc24a6
slc37a3
sulf1
tdt
trpc5
trpv3