TIMP4

Gene Name		TIMP metallopeptidase inhibitor 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Extracellular Space Sarcomere
	Molecular Function	Protease Binding Metalloendopeptidase Inhibitor Activity Metal Ion Binding
	Biological Process	Central Nervous System Development Biological_process Response To Hormone Negative Regulation Of Endopeptidase Activity Response To Lipopolysaccharide Response To Cytokine Response To Drug Ovulation Cycle Response To Peptide Hormone Negative Regulation Of Metalloenzyme Activity Negative Regulation Of Membrane Protein Ectodomain Proteolysis
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: MMP14 MMP2
Entrez ID		7079
HPRD ID		03557
Ensembl ID		ENSG00000157150
Uniprot IDs		Q99727
PDB IDs
Enriched GO Terms of Interacting Partners?		Endodermal Cell Differentiation Endoderm Formation Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Endoderm Development Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Formation Of Primary Germ Layer Gastrulation Skeletal System Morphogenesis Ossification Response To Hypoxia Angiogenesis Extracellular Matrix Organization Extracellular Structure Organization Blood Vessel Morphogenesis Blood Vessel Development Vasculature Development Skeletal System Development Astrocyte Cell Migration Intramembranous Ossification Chondrocyte Proliferation Embryonic Morphogenesis Bone Trabecula Formation Blood Vessel Maturation Craniofacial Suture Morphogenesis Cardiovascular System Development Bone Trabecula Morphogenesis Endothelial Cell Proliferation Negative Regulation Of Focal Adhesion Assembly Organ Morphogenesis Anatomical Structure Formation Involved In Morphogenesis Response To Abiotic Stimulus Embryo Development Single Organism Reproductive Process Locomotion Face Morphogenesis Negative Regulation Of Cell-matrix Adhesion Reproductive Process Head Morphogenesis Endochondral Ossification Regulation Of Focal Adhesion Assembly Trabecula Morphogenesis Movement Of Cell Or Subcellular Component Face Development Proteolysis Negative Regulation Of Cell-substrate Adhesion Body Morphogenesis Regulation Of Cell Junction Assembly
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