TEP1

Gene Name		telomerase-associated protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Telomerase Holoenzyme Complex Cytoplasm Nuclear Matrix Ribonucleoprotein Complex
	Molecular Function	Telomerase Activity RNA Binding ATP Binding
	Biological Process	Telomere Maintenance Via Recombination RNA-dependent DNA Replication
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: ATN1 PRKCA TERT TP53
Entrez ID		7011
HPRD ID		03404
Ensembl ID		ENSG00000129566
Uniprot IDs		Q99973
PDB IDs
Enriched GO Terms of Interacting Partners?		Replicative Senescence Neuron Apoptotic Process Neuron Death Cell Aging Negative Regulation Of Cellular Metabolic Process Cellular Response To Light Stimulus Chromatin Organization Positive Regulation Of Dense Core Granule Biogenesis Negative Regulation Of Production Of SiRNA Involved In RNA Interference Cellular Response To Radiation Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Chromosome Organization Negative Regulation Of Macromitophagy Negative Regulation Of RNA Interference Histone H3-T6 Phosphorylation Transcription, RNA-templated Oligodendrocyte Apoptotic Process Cell Death Death Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Peptidyl-tyrosine Phosphorylation Gene Expression Negative Regulation Of Helicase Activity Telomere Formation Via Telomerase Age-dependent Telomere Shortening Negative Regulation Of Signaling Positive Regulation Of Signal Transduction Telomere Maintenance Via Telomere Shortening Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Cycle Regulation Of Apoptotic Process Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Positive Regulation Of Cellular Component Biogenesis Regulation Of Cell Death Mitochondrial DNA Repair Telomere Assembly Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Aging Response To Light Stimulus Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment
Tagcloud ?		anticancer catalytic cloned compensate division elucidated encoding erosion fusions generally homolog immortality length neoplasms p80 protection repeat repeats repressed ribonucleoprotein telomerase telomere telomeric terc terf1 terf2 tert upregulated withdrawal