SURF4

Description		surfeit 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Plasma Membrane Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle Nuclear Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Azurophil Granule Membrane Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Cargo Receptor Activity COPII Receptor Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Positive Regulation Of Organelle Organization Protein Transport Regulation Of Lipid Transport Protein Exit From Endoplasmic Reticulum Early Endosome To Golgi Transport Lipoprotein Transport Lipid Homeostasis COPII-coated Vesicle Cargo Loading Lipid Export From Cell
Pathways		Neutrophil degranulation COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Malaria ( 31844061)
Interacting Genes		4 interacting genes: CEBPA MTNR1A STING1 VKORC1
Entrez ID		6836
HPRD ID		01715
Ensembl ID		ENSG00000148248
Uniprot IDs		B7Z1G8 B7Z7A8 O15260
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Cyclic-di-GMP Binding STING Complex 2',3'-cyclic GMP-AMP Binding CHOP-C/EBP Complex RNA Polymerase II-specific DNA-binding Transcription Factor Binding White Fat Cell Proliferation Melatonin Receptor Activity Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Response To Phenylpropanoid Proton Channel Activity Fat Cell Proliferation Positive Regulation Of CGAS/STING Signaling Pathway Response To Lithium Ion Transcription By RNA Polymerase I Urea Metabolic Process Regulation Of Hematopoietic Stem Cell Proliferation Cellular Response To Lithium Ion HMG Box Domain Binding Nitrogen Cycle Metabolic Process Positive Regulation Of Multicellular Organismal Process White Fat Cell Differentiation Regulation Of Inflammatory Response Cellular Response To Cytokine Stimulus Urea Cycle Interleukin-6-mediated Signaling Pathway STAT Family Protein Binding Osteoblast Development Hormone Binding Quinone Binding Peptidyl-glutamic Acid Modification Vitamin K Metabolic Process Protein Localization To Endoplasmic Reticulum Cellular Response To Exogenous DsRNA Positive Regulation Of Defense Response Positive Regulation Of Type I Interferon-mediated Signaling Pathway Mating Behavior Cellular Response To DsRNA Reticulophagy Serine/threonine Protein Kinase Complex Brown Fat Cell Differentiation Granulocyte Differentiation Positive Regulation Of Macrophage Activation
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