SLC22A3

Gene Name		solute carrier family 22 (organic cation transporter), member 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Dopamine Transmembrane Transporter Activity Protein Binding Organic Cation Transmembrane Transporter Activity Quaternary Ammonium Group Transmembrane Transporter Activity Toxin Transporter Activity
	Biological Process	Drug Transmembrane Transport Organic Cation Transport Quaternary Ammonium Group Transport Dopamine Transport Regulation Of Appetite Small Molecule Metabolic Process Histamine Uptake Transmembrane Transport Ammonium Transmembrane Transport Toxin Transport
Pathways		Organic cation transport Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Abacavir transmembrane transport Organic cation/anion/zwitterion transport SLC-mediated transmembrane transport Abacavir transport and metabolism
Drugs
Diseases
GWAS		Colorectal cancer ( 21242260) Coronary heart disease ( 19198611) Lp (a) levels ( 21900290) Prostate cancer ( 18264097) Response to hepatitis C treatment ( 22095909)
Protein-protein Interactions		1 interactors: PDZD3
Entrez ID		6581
HPRD ID		05328
Ensembl ID		ENSG00000146477
Uniprot IDs		O75751
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of CGMP Biosynthetic Process Negative Regulation Of Guanylate Cyclase Activity CGMP-mediated Signaling Receptor Guanylyl Cyclase Signaling Pathway Regulation Of CGMP Biosynthetic Process Negative Regulation Of Lyase Activity Cyclic-nucleotide-mediated Signaling Regulation Of CGMP Metabolic Process Negative Regulation Of Nucleotide Metabolic Process Water Transport Fluid Transport Regulation Of Cyclase Activity Second-messenger-mediated Signaling Response To Toxic Substance
Tagcloud ?		anat asmt characterise circumventricular cldn3 col11a1 cvos epcam ependyma ependymocytes lcm microdissection organum ovlt peculiar periventricular pineal ren1 sco sfo specialised subcommissural subfornical terminalis tph transcriptomes vasculosum ventricles vestigial