SLC8A3

Description		solute carrier family 8 member A3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Cytosol Microtubule Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Sarcoplasm Axon Dendrite Neuromuscular Junction Sarcolemma Cell Projection Neuronal Cell Body Dendritic Spine Perikaryon Axon Terminus Synapse Postsynaptic Membrane Perinuclear Region Of Cytoplasm Anchoring Junction Postsynapse
	Molecular Function	Calcium:sodium Antiporter Activity Protein Binding Calmodulin Binding Antiporter Activity Calcium:monoatomic Cation Antiporter Activity Metal Ion Binding Calcium:monoatomic Cation Antiporter Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration
	Biological Process	Hematopoietic Progenitor Cell Differentiation Monoatomic Ion Transport Sodium Ion Transport Calcium Ion Transport Mitochondrial Calcium Ion Transmembrane Transport Intracellular Calcium Ion Homeostasis Cell Communication Learning Or Memory Learning Memory Regulation Of Skeletal Muscle Contraction Telencephalon Development Metal Ion Transport Sodium Ion Transmembrane Transport Myelination Oligodendrocyte Differentiation Synapse Organization Mitochondrial Calcium Ion Homeostasis Transmembrane Transport Long-term Synaptic Potentiation Calcium Ion Transport Into Cytosol Calcium Ion Transmembrane Transport Cellular Response To CAMP Cellular Response To Hypoxia Calcium Ion Import Across Plasma Membrane Modulation Of Excitatory Postsynaptic Potential Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Negative Regulation Of Intracellular Signal Transduction Regulation Of Cardiac Conduction Calcium Ion Export Across Plasma Membrane
Pathways		Reduction of cytosolic Ca++ levels Sodium/Calcium exchangers Ion homeostasis Mitochondrial calcium ion transport
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Corneal curvature ( 22969067) Cystic fibrosis severity ( 21602797) Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: GJA8 PPP3CB YWHAB YWHAE YWHAQ
Entrez ID		6547
HPRD ID		09723
Ensembl ID		ENSG00000100678
Uniprot IDs		B3KU59 P57103
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Monoatomic Ion Transmembrane Transport Negative Regulation Of Transport Negative Regulation Of Monoatomic Ion Transport Phosphoserine Residue Binding Negative Regulation Of Transmembrane Transport Protein Targeting Protein Domain Specific Binding Regulation Of Monoatomic Ion Transmembrane Transport Negative Regulation Of Calcium Ion Transmembrane Transport Phosphoprotein Binding Protein Phosphatase Inhibitor Activity Protein Sequestering Activity Substantia Nigra Development Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Calcium Ion Transport Enzyme Binding Regulation Of Monoatomic Ion Transport Neural Nucleus Development Focal Adhesion Regulation Of Protein Transport Negative Regulation Of Cation Transmembrane Transport Regulation Of Establishment Of Protein Localization Regulation Of Cellular Localization Regulation Of Transport Melanosome Regulation Of Nucleocytoplasmic Transport Histone Deacetylase Binding Regulation Of Heart Rate By Hormone Transmembrane Transporter Binding Regulation Of Calcium Ion Transmembrane Transport Regulation Of Intracellular Protein Transport Regulation Of Protein Localization To Nucleus Positive Regulation Of Lysosome Organization Intracellular Signaling Cassette Calmodulin-dependent Protein Phosphatase Activity Regulation Of Protein Localization Regulation Of Heart Rate By Chemical Signal Negative Regulation Of Calcium Ion Export Across Plasma Membrane Negative Regulation Of Protein Localization Gap Junction-mediated Intercellular Transport Negative Regulation Of Calcium Ion Import Across Plasma Membrane Regulation Of Calcium Ion Transport Calcineurin Complex Regulation Of Calcium Ion Export Across Plasma Membrane Locomotion Involved In Locomotory Behavior Positive Regulation Of Protein Transport Positive Regulation Of Toll-like Receptor Signaling Pathway Protein Phosphatase 2B Binding Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Intracellular Transport
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