SLC6A4

Gene Name		solute carrier family 6 (neurotransmitter transporter), member 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Endosome Membrane Endomembrane System Neuron Projection Membrane Raft
	Molecular Function	Serotonin:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Serotonin Transmembrane Transporter Activity Myosin Binding Syntaxin-1 Binding Rab GTPase Binding Cocaine Binding Protein Homodimerization Activity Nitric-oxide Synthase Binding Actin Filament Binding
	Biological Process	Response To Hypoxia Serotonin Transport Response To Nutrient Memory Circadian Rhythm Response To Toxic Substance Positive Regulation Of Gene Expression Monoamine Transport Thalamus Development Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Negative Regulation Of Synaptic Transmission, Dopaminergic Response To Estradiol Social Behavior Vasoconstriction Response To Drug Sperm Ejaculation Negative Regulation Of Neuron Differentiation Positive Regulation Of Cell Cycle Negative Regulation Of Organ Growth Brain Morphogenesis Protein Oligomerization Protein Homooligomerization Serotonin Uptake Transmembrane Transport Cellular Response To Retinoic Acid Cellular Response To CGMP
Pathways
Drugs		Fluvoxamine Phentermine Tramadol Citalopram Venlafaxine Atomoxetine Amitriptyline Protriptyline Methylphenidate Imipramine Fluoxetine Duloxetine Dextromethorphan Nortriptyline Amoxapine Fenfluramine Mazindol Trazodone Verapamil Paroxetine Trimipramine Minaprine Pseudoephedrine Cocaine Sertraline Sibutramine Chlorpheniramine Doxepin Nefazodone Desipramine Escitalopram Dexfenfluramine Clomipramine Ephedra MMDA 3,4-Methylenedioxymethamphetamine 4-Methoxyamphetamine Methamphetamine Zimelidine Amineptine Milnacipran Mianserin Tapentadol Desvenlafaxine Dexmethylphenidate Levomilnacipran
Diseases
GWAS
Protein-protein Interactions		4 interactors: CALR CANX STX1A YBX1
Entrez ID		6532
HPRD ID		01640
Ensembl ID		ENSG00000108576
Uniprot IDs		B2R7Y7 P31645
PDB IDs
Enriched GO Terms of Interacting Partners?		Chaperone-mediated Protein Folding Protein N-linked Glycosylation Via Asparagine Synaptic Vesicle Transport Protein N-linked Glycosylation Peptide Antigen Assembly With MHC Class I Protein Complex Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Establishment Of Vesicle Localization Post-translational Protein Modification Vesicle Localization Antigen Processing And Presentation Of Peptide Antigen Sequestering Of Calcium Ion Regulation Of Cell Division CRD-mediated MRNA Stabilization Protein Transport Protein Folding Vesicle-mediated Transport Antigen Processing And Presentation Establishment Of Protein Localization Aging Positive Regulation Of Dendritic Cell Chemotaxis Establishment Of Organelle Localization Protein Glycosylation Macromolecule Glycosylation Glycosylation Receptor-mediated Endocytosis Glucocorticoid Receptor Signaling Pathway Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Regulation Of Vesicle-mediated Transport Glycoprotein Biosynthetic Process Sequestering Of Metal Ion Organelle Localization Synaptic Vesicle Fusion To Presynaptic Membrane Protein Maturation By Protein Folding Protein Localization Glycoprotein Metabolic Process Posttranscriptional Regulation Of Gene Expression Establishment Of Localization In Cell Response To Gravity Positive Regulation Of Neurotransmitter Secretion Secretion By Cell Cellular Response To Lithium Ion Negative Regulation Of Striated Muscle Cell Differentiation Synaptic Transmission Cellular Localization Glutamate Secretion Secretion Cortical Actin Cytoskeleton Organization Endocytosis MRNA Stabilization
Tagcloud ?		adjective analyze anxiety authors bp check genotype genotypes homogeneous htt httlpr inventory list mao measuring menopausal mood nevertheless poland polymorphism possibility postmenopausal promoter prove region respondents slight trait vntr