PYCRL

Gene Name		pyrroline-5-carboxylate reductase-like
Image		No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	Pyrroline-5-carboxylate Reductase Activity
	Biological Process	Oxidation-reduction Process L-proline Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Rhegmatogenous retinal detachment ( 23585552)
Protein-protein Interactions		3 interactors: LBP PRMT6 SDCBP
Entrez ID		65263
HPRD ID		15196
Ensembl ID		ENSG00000104524
Uniprot IDs		Q53H96
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Leukocyte Chemotaxis Involved In Inflammatory Response Histone H3-R2 Methylation Lipopolysaccharide Transport Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Respiratory Burst Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Opsonization Regulation Of Respiratory Burst Macrophage Activation Involved In Immune Response Substrate-dependent Cell Migration, Cell Extension Positive Regulation Of Macrophage Activation Positive Regulation Of Toll-like Receptor Signaling Pathway Histone H4-R3 Methylation Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Cellular Response To Lipoteichoic Acid Detection Of Molecule Of Bacterial Origin Chemotaxis Peptidyl-arginine N-methylation Leukocyte Migration Involved In Inflammatory Response Regulation Of Tumor Necrosis Factor Biosynthetic Process Histone Arginine Methylation Peptidyl-arginine Methylation Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of Organelle Assembly Regulation Of Macrophage Activation Positive Regulation Of Granulocyte Chemotaxis Negative Regulation Of Growth Of Symbiont In Host Detection Of Biotic Stimulus Cell Migration Regulation Of Neutrophil Chemotaxis Macrophage Activation Regulation Of Neutrophil Migration Positive Regulation Of Interleukin-8 Production Cell Motility Defense Response To Gram-negative Bacterium Regulation Of Granulocyte Chemotaxis Substrate-dependent Cell Migration Lipopolysaccharide-mediated Signaling Pathway Acute-phase Response Negative Regulation Of Tumor Necrosis Factor Production Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Positive Regulation Of Chemokine Production Carbohydrate Derivative Transport Cellular Defense Response
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