PYCR3

Description		pyrroline-5-carboxylate reductase 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Intercellular Bridge Mitotic Spindle
	Molecular Function	Pyrroline-5-carboxylate Reductase Activity Protein Binding Oxidoreductase Activity Identical Protein Binding
	Biological Process	Amino Acid Biosynthetic Process L-proline Biosynthetic Process
Pathways		Glutamate and glutamine metabolism
Drugs		Proline
Diseases
GWAS
Interacting Genes		11 interacting genes: AKT1 BAG4 CDKN2B FXR1 FXR2 HOXA1 LBP NTAQ1 PRMT6 PSMB1 SDCBP
Entrez ID		65263
HPRD ID		15196
Ensembl ID		ENSG00000104524
Uniprot IDs		A0A0A0MQS1 B4DGI7 Q53H96
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of MRNA Metabolic Process Positive Regulation Of Fibroblast Migration Translation Regulator Activity Positive Regulation Of Translation Dentate Gyrus Development Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of MRNA Stability Localization Within Membrane Postsynapse Regulation Of Fibroblast Migration Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Regulation Of RNA Stability Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Cell Communication Nucleus Regulation Of Signaling Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Presynaptic Modulation Of Chemical Synaptic Transmission Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Locomotion Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Metabolic Process Cell Surface Pattern Recognition Receptor Signaling Pathway Regulation Of TRNA Methylation Response To Epidermal Growth Factor Semicircular Canal Formation Interleukin-5 Receptor Complex Regulation Of Neuronal Synaptic Plasticity Negative Regulation Of MRNA Modification Protein-N-terminal Glutamine Amidohydrolase Activity Histone H2AR3 Methyltransferase Activity Cellular Senescence Negative Regulation Of Tumor Necrosis Factor Production Regulation Of Multicellular Organismal Process Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Regulation Of Signal Transduction Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Protein Localization To Lysosome Translational Initiation Regulation Of Behavior Abducens Nerve Formation
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