STIL

Gene Name		SCL/TAL1 interrupting locus
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytosol
	Molecular Function	Protein Binding
	Biological Process	Embryonic Axis Specification In Utero Embryonic Development Neural Tube Closure Heart Looping Mitotic Spindle Organization Smoothened Signaling Pathway Determination Of Left/right Symmetry Cell Proliferation Neural Tube Development Forebrain Development Notochord Development Floor Plate Development Multicellular Organism Growth Negative Regulation Of Apoptotic Process Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Centrosome Duplication Cilium Morphogenesis Mitotic Spindle Checkpoint Protein Localization To Centrosome
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: PIN1
Entrez ID		6491
HPRD ID		01627
Ensembl ID		ENSG00000123473
Uniprot IDs		E9PSF2 Q15468
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Type I Interferon Production Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Cytokinesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Protein Peptidyl-prolyl Isomerization Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Type I Interferon Production Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Mitotic Nuclear Division Positive Regulation Of Protein Ubiquitination Negative Regulation Of MAPK Cascade Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of ERK1 And ERK2 Cascade Regulation Of Protein Ubiquitination Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility Negative Regulation Of Cellular Component Movement Positive Regulation Of Rho GTPase Activity Negative Regulation Of Locomotion Regulation Of Cell Division Regulation Of Rho GTPase Activity Regulation Of Rho Protein Signal Transduction
Tagcloud ?		ablation abscence beam centriole centrioles centrosomes cilia compatible consisting contain defective division embryonic explains gastrulation gestation hedgehog impairs lethality machinery mammalian microcephaly mid novo organelles pair precise scanning templated