GAREM

Gene Name		GRB2 associated, regulator of MAPK1
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Gene Ontology Annotations	Cellular Component	Plasma Membrane
	Molecular Function	Protein Binding Proline-rich Region Binding
	Biological Process	Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Proliferation Positive Regulation Of Cell Division Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Epidermal Growth Factor Stimulus
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: CRKL GRB2
Entrez ID		64762
HPRD ID		12685
Ensembl ID		ENSG00000141441
Uniprot IDs		Q9H706
PDB IDs		2DKZ
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of MAPK Cascade Small GTPase Mediated Signal Transduction Parathyroid Gland Development Branching Involved In Labyrinthine Layer Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Labyrinthine Layer Morphogenesis Embryonic Placenta Morphogenesis Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Receptor Internalization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Negative Regulation Of ERBB Signaling Pathway Cellular Response To Stress Labyrinthine Layer Development Cellular Response To Ionizing Radiation Thymus Development Activation Of MAPKK Activity Regulation Of Intracellular Signal Transduction Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Intracellular Signal Transduction T Cell Costimulation Cellular Response To Organic Substance Regulation Of ERBB Signaling Pathway Receptor Metabolic Process JNK Cascade Positive Regulation Of Reactive Oxygen Species Metabolic Process Signal Transduction In Response To DNA Damage
Tagcloud ?		3epsilon adaptor egf encoded erk eventually grb2 homologues localization make mapk1 named neuroblastoma nucleus organs phosphorylated recruited regulates regulator sh shp2 subtype subtypes sy5y tyr tyrosines ubiquitously