BLVRB

Description		biliverdin reductase B
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Biliverdin Reductase [NAD(P)H] Activity Protein Binding Oxidoreductase Activity Transferase Activity Peptidyl-cysteine S-nitrosylase Activity Riboflavin Reductase (NADPH) Activity FMN Reductase (NADPH) Activity FMN Reductase (NADH) Activity
	Biological Process	Insulin Receptor Signaling Pathway Megakaryocyte Differentiation Heme Catabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway
Pathways		Heme degradation Cytoprotection by HMOX1
Drugs		Riboflavin NADH Biliverdine IX Alpha Flavin mononucleotide Nicotinamide adenine dinucleotide phosphate Lumichrome Mesobiliverdin IV alpha
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		4 interacting genes: ANXA10 HMOX1 ORM1 RPL31
Entrez ID		645
HPRD ID		02967
Ensembl ID		ENSG00000090013
Uniprot IDs		P30043 V9HWI1
PDB IDs		1HDO 1HE2 1HE3 1HE4 1HE5 5OOG 5OOH 6OPL 7ER6 7ER7 7ER8 7ER9 7ERA 7ERB 7ERC 7ERD 7ERE 8ELL 8ELM 8K4K
Enriched GO Terms of Interacting Partners?		Heme Oxidation Smooth Muscle Hyperplasia Heme Oxygenase (decyclizing) Activity Wound Healing Involved In Inflammatory Response Cellular Response To Cisplatin Smooth Muscle Adaptation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Porphyrin-containing Compound Catabolic Process Negative Regulation Of Cytokine Production Erythrocyte Homeostasis Response To Cisplatin Heme Catabolic Process
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