MMP25

Description		matrix metallopeptidase 25
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Extracellular Matrix Specific Granule Membrane Side Of Membrane
	Molecular Function	Metalloendopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Proteolysis Inflammatory Response Extracellular Matrix Organization Collagen Catabolic Process Hard Palate Development
Pathways		Activation of Matrix Metalloproteinases Neutrophil degranulation
Drugs		Marimastat Fenofibrate Fenofibric acid
Diseases
GWAS
Interacting Genes		3 interacting genes: CLU MEOX2 MMP2
Entrez ID		64386
HPRD ID		07090
Ensembl ID		ENSG00000008516
Uniprot IDs		Q9NPA2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Spherical High-density Lipoprotein Particle Negative Regulation Of Activation Of Membrane Attack Complex Regulation Of Apoptotic Signaling Pathway Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Perinuclear Endoplasmic Reticulum Lumen Positive Regulation Of Neurofibrillary Tangle Assembly Microglial Cell Proliferation Protein Import Positive Regulation Of Inclusion Body Assembly Regulation Of Neuron Apoptotic Process Negative Regulation Of Complement-dependent Cytotoxicity Central Nervous System Myelin Maintenance Regulation Of Intrinsic Apoptotic Signaling Pathway Neurofibrillary Tangle Chromaffin Granule Regulation Of Neuronal Signal Transduction Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Amyloid Fibril Formation Immune Complex Clearance Angiogenesis Somite Specification Intramembranous Ossification Ovulation From Ovarian Follicle Luteinization Blood Vessel Maturation Parturition Peripheral Nervous System Axon Regeneration Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Trophoblast Cell Migration Cellular Response To UV-A Bone Trabecula Formation Protein Carrier Chaperone Negative Regulation Of Amyloid Fibril Formation Protein Targeting To Vacuole Involved In Autophagy Regulation Of Complement-dependent Cytotoxicity Negative Regulation Of Complement Activation Response To Misfolded Protein Response To UV-A Ovulation Negative Regulation Of Vasoconstriction Positive Regulation Of Programmed Cell Death Apical Dendrite Myelin Maintenance Negative Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Apoptotic Process Regulation Of Amyloid Fibril Formation Reverse Cholesterol Transport
Tagcloud ?