ABCG5

Gene Name		ATP-binding cassette, sub-family G (WHITE), member 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Apical Plasma Membrane ATP-binding Cassette (ABC) Transporter Complex Receptor Complex
	Molecular Function	Protein Binding ATP Binding ATPase Activity Cholesterol Transporter Activity Protein Heterodimerization Activity
	Biological Process	Response To Nutrient Excretion Response To Ionizing Radiation Negative Regulation Of Intestinal Phytosterol Absorption Sterol Transport Intestinal Cholesterol Absorption Cholesterol Efflux Response To Drug Cholesterol Homeostasis Small Molecule Metabolic Process Negative Regulation Of Intestinal Cholesterol Absorption Transmembrane Transport
Pathways		Metabolism of lipids and lipoproteins ABC-family proteins mediated transport Lipid digestion, mobilization, and transport Trafficking of dietary sterols ABCA transporters in lipid homeostasis
Drugs
Diseases
GWAS		Cholesterol, total ( 19060911 20686565) LDL cholesterol ( 19060911 20686565) Lipid metabolism phenotypes ( 19936222)
Protein-protein Interactions		1 interactors: ABCG8
Entrez ID		64240
HPRD ID		05678
Ensembl ID		ENSG00000138075
Uniprot IDs		Q9H222
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Intestinal Cholesterol Absorption Negative Regulation Of Intestinal Phytosterol Absorption Intestinal Cholesterol Absorption Regulation Of Intestinal Cholesterol Absorption Negative Regulation Of Cholesterol Transport Lipid Digestion Intestinal Absorption Negative Regulation Of Lipid Transport Cholesterol Efflux Regulation Of Cholesterol Transport Excretion Sterol Transport Cholesterol Transport Cholesterol Homeostasis Sterol Homeostasis Phospholipid Transport Regulation Of Lipid Transport Lipid Homeostasis Digestion Response To Nutrient Lipid Transport Lipid Localization Negative Regulation Of Transport Response To Nutrient Levels Organic Anion Transport Response To Extracellular Stimulus Response To Drug Anion Transport
Tagcloud ?		abca1 abcg8 atorvastatin causal challenging chow excised fads1 gwas hfd hypertensive list loci lpl madd nominally nr1h3 orthologs overlapped pcsk9 pltp qpcr qtl responded spontaneously stac3 staged suggestive timd4