DPEP2

Description		dipeptidase 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Side Of Membrane
	Molecular Function	Peptidase Activity Metallopeptidase Activity Hydrolase Activity Dipeptidase Activity Metal Ion Binding Metallodipeptidase Activity
	Biological Process	Proteolysis Lipid Metabolic Process Leukotriene Metabolic Process Leukotriene D4 Catabolic Process
Pathways		Synthesis of Leukotrienes (LT) and Eoxins (EX) Aflatoxin activation and detoxification LTC4-CYSLTR mediated IL4 production
Drugs
Diseases
GWAS		HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 29403010) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Triglyceride levels in current drinkers ( 30698716)
Interacting Genes		1 interacting genes: NLGN3
Entrez ID		64174
HPRD ID		07011
Ensembl ID		ENSG00000167261
Uniprot IDs		Q9H4A9
PDB IDs
Enriched GO Terms of Interacting Partners?		Neurexin Family Protein Binding Asymmetric, Glutamatergic, Excitatory Synapse Regulation Of Respiratory Gaseous Exchange By Nervous System Process Inhibitory Postsynaptic Potential Positive Regulation Of Glutamate Receptor Signaling Pathway Rhythmic Synaptic Transmission Postsynaptic Membrane Assembly Postsynaptic Membrane Organization Presynaptic Membrane Assembly Regulation Of Glutamate Receptor Signaling Pathway Symmetric, GABA-ergic, Inhibitory Synapse Neuron To Neuron Synapse Presynapse Assembly Presynaptic Membrane Organization Regulation Of Respiratory System Process Neuron Cell-cell Adhesion Presynapse Organization Vocalization Behavior Regulation Of Respiratory Gaseous Exchange Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Transmission, Glutamatergic Excitatory Synapse Synaptic Vesicle Endocytosis Presynaptic Endocytosis Axon Extension Modulation Of Excitatory Postsynaptic Potential Social Behavior Membrane Assembly Positive Regulation Of Synapse Assembly Regulation Of Synaptic Transmission, Glutamatergic Endocytic Vesicle Scaffold Protein Binding Neuron Projection Extension Vesicle-mediated Transport In Synapse Cell Adhesion Molecule Binding Synapse Assembly Regulation Of Postsynaptic Membrane Potential Positive Regulation Of Cell Junction Assembly Developmental Cell Growth Regulation Of Nervous System Process Developmental Growth Involved In Morphogenesis Positive Regulation Of Synaptic Transmission Adult Behavior Learning Regulation Of Synapse Assembly Receptor-mediated Endocytosis Presynapse Postsynaptic Membrane Learning Or Memory Regulation Of Cell Junction Assembly
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