CRLF2

Description		cytokine receptor like factor 2
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Membrane Receptor Complex
	Molecular Function	Cytokine Receptor Activity Coreceptor Activity Cytokine Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Positive Regulation Of Interleukin-5 Production Positive Regulation Of Mast Cell Activation Positive Regulation Of Receptor Signaling Pathway Via STAT
Pathways		Interleukin-7 signaling Interleukin-7 signaling
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: IL7R JAK2 TSLP
Entrez ID		64109
HPRD ID		02288
Ensembl ID		ENSG00000205755
Uniprot IDs		Q9HC73
PDB IDs		5J11 5J12
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Receptor Signaling Pathway Via STAT Interleukin-7-mediated Signaling Pathway Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Cytokine-mediated Signaling Pathway Positive Regulation Of Cell Activation Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Cell Activation Cell Surface Receptor Signaling Pathway Via JAK-STAT Cell Surface Receptor Signaling Pathway Via STAT Positive Regulation Of Cell Population Proliferation Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Histone H3Y41 Kinase Activity Nuclear Receptor-mediated Mineralocorticoid Signaling Pathway Symbiont-induced Defense-related Programmed Cell Death Interleukin-35-mediated Signaling Pathway Positive Regulation Of Chemokine (C-C Motif) Ligand 1 Production Positive Regulation Of Immune System Process T Cell Differentiation Immune Response Response To Other Organism Positive Regulation Of Gene Expression Hemopoiesis Interleukin-7 Receptor Activity Regulation Of Postsynapse To Nucleus Signaling Pathway Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Interleukin-7 Receptor Binding Defense Response Response To External Biotic Stimulus Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Adaptive Immune Response Interleukin-12 Receptor Complex Positive Regulation Of Skeletal Muscle Cell Proliferation Positive Regulation Of Growth Hormone Receptor Signaling Pathway Positive Regulation Of Granulocyte Colony-stimulating Factor Production Positive Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Positive Regulation Of T Cell Activation Lymphocyte Differentiation Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway Response To Interleukin-12 Interleukin-23 Receptor Complex Granulocyte Macrophage Colony-stimulating Factor Receptor Complex Activation Of Janus Kinase Activity Positive Regulation Of Signal Transduction Positive Regulation Of Leukocyte Cell-cell Adhesion Adaptive Immune Response Positive Regulation Of Multicellular Organismal Process Defense Response To Bacterium
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