PCIF1

Description		phosphorylated CTD interacting factor 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	Methyltransferase Activity MRNA (2'-O-methyladenosine-N6-)-methyltransferase Activity Transferase Activity RNA Polymerase II C-terminal Domain Binding S-adenosyl-L-methionine Binding RNA Polymerase II C-terminal Domain Phosphoserine Binding
	Biological Process	MRNA Processing Regulation Of Translation Negative Regulation Of Translation Methylation Positive Regulation Of Translation
Pathways
Drugs
Diseases
GWAS		Abdominal aortic aneurysm ( 27899403) Coronary artery disease ( 29212778) Gut microbiota (functional units) ( 27694959) HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Hemoglobin levels ( 26366553) High density lipoprotein cholesterol levels ( 29403010 33339817) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Metabolic syndrome ( 31589552) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) Serum alkaline phosphatase levels ( 33547301) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Triglyceride levels ( 30698716 33339817 29403010) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		4 interacting genes: APP PDX1 POLR2A UBC
Entrez ID		63935
HPRD ID		12779
Ensembl ID		ENSG00000100982
Uniprot IDs		Q9H4Z3
PDB IDs		2JX8 6IRV 6IRW
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Cellular Response To Acadesine Promoter-specific Chromatin Binding Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Intrinsic Apoptotic Signaling Pathway Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Chlorate Type B Pancreatic Cell Apoptotic Process RNA-directed RNA Polymerase Activity RNA-templated Transcription Regulation Of Spontaneous Synaptic Transmission Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Regulation Of Toll Signaling Pathway Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Protein Transport Glucose Mediated Signaling Pathway Positive Regulation Of Type B Pancreatic Cell Proliferation Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Microfibril Binding Axon Choice Point Recognition Transdifferentiation Response To Iron(II) Ion 5'-3' RNA Polymerase Activity Transcription By RNA Polymerase II
Tagcloud ?