SCN10A

Gene Name		sodium channel, voltage gated, type X alpha subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Voltage-gated Sodium Channel Complex C-fiber Extracellular Vesicular Exosome
	Molecular Function	Voltage-gated Sodium Channel Activity
	Biological Process	Regulation Of Heart Rate Sodium Ion Transport Sensory Perception Neuronal Action Potential Sensory Perception Of Pain Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Regulation Of Cardiac Muscle Contraction Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Membrane Depolarization During Action Potential AV Node Cell To Bundle Of His Cell Communication Bundle Of His Cell To Purkinje Myocyte Communication
Pathways		Interaction between L1 and Ankyrins Axon guidance L1CAM interactions
Drugs		Lidocaine Ropivacaine Bupivacaine Hexylcaine Dibucaine Dyclonine Procaine Proparacaine Oxybuprocaine Cocaine Mepivacaine Levobupivacaine Benzocaine Chloroprocaine Orphenadrine Lacosamide
Diseases
GWAS		Atrioventricular conduction ( 21041692) Electrocardiographic conduction measures ( 23463857) Electrocardiographic traits ( 20062061 20062063) PR interval ( 20062060 23139255) Systemic lupus erythematosus ( 23273568) Ventricular conduction ( 21076409)
Protein-protein Interactions		2 interactors: ACTB SCLT1
Entrez ID		6336
HPRD ID		09188
Ensembl ID		ENSG00000185313
Uniprot IDs		Q9Y5Y9
PDB IDs
Enriched GO Terms of Interacting Partners?		Clustering Of Voltage-gated Sodium Channels Neuronal Ion Channel Clustering Cell Projection Morphogenesis Membrane Organization Cell Part Morphogenesis Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Neuron Maturation Substantia Nigra Development Platelet Aggregation Generation Of Neurons Neural Nucleus Development 'de Novo' Posttranslational Protein Folding Neurogenesis Retina Homeostasis 'de Novo' Protein Folding ATP-dependent Chromatin Remodeling Cell Development Cellular Component Assembly Midbrain Development Adherens Junction Organization Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Nervous System Development Anatomical Structure Morphogenesis Cell Maturation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway
Tagcloud ?		arrhythmias cardiac clustered coactivator colocalized conduction congenital contraction disrupts electrical enhancer enhancers functionally gata4 helps humans impulse nkx2 noncoding occupation perturbations predisposition relies repressed scn5a snp tbx3 tbx5 uncovering