RREB1

Gene Name		ras responsive element binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Body Nuclear Speck Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Ras Protein Signal Transduction Multicellular Organismal Development Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Wound Healing, Spreading Of Epidermal Cells Positive Regulation Of Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS		Age-related macular degeneration ( 20385826) Fasting glucose-related traits (interaction with BMI) ( 22581228) Multiple sclerosis ( 21833088) Urate levels ( 20884846 23263486) Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-protein Interactions		2 interactors: HIST3H3 NEUROD1
Entrez ID		6239
HPRD ID		03733
Ensembl ID		ENSG00000124782
Uniprot IDs		Q92766
PDB IDs
Enriched GO Terms of Interacting Partners?		Pancreatic A Cell Fate Commitment Regulation Of Intestinal Epithelial Structure Maintenance Pancreatic PP Cell Fate Commitment Amacrine Cell Differentiation Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Pancreatic A Cell Differentiation Positive Regulation Of Transcription Regulatory Region DNA Binding Nitric Oxide Mediated Signal Transduction Dentate Gyrus Development Negative Regulation Of JAK-STAT Cascade Epithelial Cell Fate Commitment Regulation Of Transcription Regulatory Region DNA Binding Enteroendocrine Cell Differentiation Signal Transduction Involved In Regulation Of Gene Expression Positive Regulation Of DNA Binding Homeostatic Process Insulin Secretion Glandular Epithelial Cell Differentiation Endocrine Pancreas Development Neural Retina Development Cellular Response To Glucose Stimulus Peptide Hormone Secretion Peptide Secretion Hippocampus Development Cellular Glucose Homeostasis Telomere Maintenance Cellular Response To Carbohydrate Stimulus Hormone Secretion Regulation Of DNA Binding Regulation Of JAK-STAT Cascade Hormone Transport Peptide Transport Pancreas Development Regulation Of Cell Cycle Arrest Limbic System Development Cerebellum Development Positive Regulation Of Binding
Tagcloud ?		11q13 6p25 atf1 braf clear confirming cytokeratins diastase epidermotropic epithelioid ewsr1 gains glycogen histologic hmb intracytoplasmic labeling melan melanoma morphologic p63 periodic perivascular rule s100 sarcoma schiff ulcerated v600e