RPS12

Gene Name		ribosomal protein S12
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Gene Ontology Annotations	Cellular Component	Cytosol Membrane Cytosolic Small Ribosomal Subunit
	Molecular Function	Structural Constituent Of Ribosome Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Type 2 diabetes nephropathy ( 21150874)
Protein-protein Interactions		2 interactors: APP IKBKG
Entrez ID		6206
HPRD ID		04714
Ensembl ID
Uniprot IDs		P25398
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Innate Immune Response Cellular Copper Ion Homeostasis Apoptotic Process Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Copper Ion Homeostasis Suckling Behavior Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Death Death Regulation Of Protein Phosphorylation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Protein Metabolic Process Mating Behavior B Cell Homeostasis Endoplasmic Reticulum Calcium Ion Homeostasis Immune Response RNA Polyadenylation Neuron Recognition Regulation Of Phosphorylation NIK/NF-kappaB Signaling Positive Regulation Of Transcription, DNA-templated Defense Response Regulation Of NIK/NF-kappaB Signaling Homeostatic Process Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Gene Expression
Tagcloud ?		apocytochrome infa l20 l22 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl2 rpl20 rpl22 rpl23 rpl33 rpoa rps11 rps18 rps3 rps8 secx ugg