BCAT1

Gene Name		branched chain amino-acid transaminase 1, cytosolic
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Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol
	Molecular Function	Branched-chain-amino-acid Transaminase Activity Identical Protein Binding L-leucine Transaminase Activity L-valine Transaminase Activity L-isoleucine Transaminase Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Cell Proliferation Branched-chain Amino Acid Biosynthetic Process Branched-chain Amino Acid Catabolic Process Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process
Pathways		Branched-chain amino acid catabolism Metabolism of amino acids and derivatives
Drugs		Pyridoxal Phosphate L-Glutamic Acid L-Leucine L-Valine L-Isoleucine N\'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE
Diseases
GWAS		Response to statin therapy ( 20339536) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Protein-protein Interactions		3 interactors: KDM1A PRMT6 SMAD5
Entrez ID		586
HPRD ID		00216
Ensembl ID		ENSG00000060982
Uniprot IDs		P54687
PDB IDs		2ABJ 2COG 2COI 2COJ
Enriched GO Terms of Interacting Partners?		Regulation Of Primitive Erythrocyte Differentiation Histone H3-R2 Methylation Myeloid Cell Differentiation Mullerian Duct Regression Histone Modification Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Transcription, DNA-templated RNA Biosynthetic Process Osteoblast Fate Commitment Positive Regulation Of Megakaryocyte Differentiation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Histone H4-R3 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Chromatin Modification Anatomical Structure Regression Granulocyte Differentiation Hemopoiesis Peptidyl-arginine N-methylation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation RNA Metabolic Process Immune System Development Cellular Protein Modification Process Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Histone Arginine Methylation Chromatin Organization Peptidyl-arginine Methylation Regulation Of Histone H3-K4 Methylation Cellular Response To BMP Stimulus Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Gene Expression Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hormone Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cell Differentiation Macromolecule Biosynthetic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Histone Lysine Demethylation Regulation Of Hormone Metabolic Process Histone Demethylation Regulation Of Erythrocyte Differentiation
Tagcloud ?		atf4 axonal believe branched cage catabolism crush ddit3 differentially dynamism eyes ganglion glaucoma highlighting ifng log2 onc optic orchestrating pathomechanisms presumably retinas revealing rgc rgcs sequenced serves silico transaminase