PZP

Gene Name		pregnancy-zone protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Female Pregnancy Negative Regulation Of Endopeptidase Activity
Pathways
Drugs
Diseases
GWAS		Non-alcoholic fatty liver disease histology (AST) ( 20708005) Obesity-related traits ( 23251661)
Protein-protein Interactions		6 interactors: CPB2 KLK3 MMP2 MMP9 TGFB1 TGFB2
Entrez ID		5858
HPRD ID		07178
Ensembl ID		ENSG00000126838
Uniprot IDs
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Face Morphogenesis Regulation Of Extracellular Matrix Organization Head Morphogenesis Face Development Negative Regulation Of Macrophage Cytokine Production Body Morphogenesis Positive Regulation Of Epithelial Cell Migration Endoderm Development Extracellular Matrix Disassembly Blood Coagulation SMAD Protein Import Into Nucleus Hemostasis Negative Regulation Of Epithelial Cell Proliferation Pathway-restricted SMAD Protein Phosphorylation Regulation Of Fibrinolysis Regulation Of Epithelial Cell Migration Skeletal System Development Regulation Of Body Fluid Levels Wound Healing Response To Wounding Cell Morphogenesis Involved In Differentiation Female Pregnancy Fibrinolysis Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Epithelial To Mesenchymal Transition Skeletal System Morphogenesis Ossification Regulation Of Epithelial Cell Proliferation Endodermal Cell Differentiation Response To Hypoxia Positive Regulation Of Secretion Positive Regulation Of Cell Migration Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Salivary Gland Morphogenesis Positive Regulation Of Cell Motility Cell Morphogenesis Salivary Gland Development Positive Regulation Of Cellular Component Movement Response To Abiotic Stimulus Positive Regulation Of Locomotion Response To Progesterone Positive Regulation Of Stem Cell Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Blood Coagulation Endoderm Formation SMAD Protein Signal Transduction Epithelial To Mesenchymal Transition Regulation Of Epithelial To Mesenchymal Transition
Tagcloud ?		alt anthropometric apoc3 cms col13a1 consent corrections efcab4b infiltration iu nafld ncan obtaining parvb patatin pnpla3 rs2073080 rs2143571 rs2228603 rs2854117 rs343062 rs6487679 rs6591182 rs738409 samm50 sequenom snps transaminase triglyceride