OSTC

Name	oligosaccharyltransferase complex non-catalytic subunit
Structure
Novel Interactors	1 novel interactors: LARP7
Interactors	6 interactors: ATP13A2 CCR9 EDA F2RL1 GPR35 TRARG1
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Oligosaccharyltransferase Complex Membrane Oligosaccharyltransferase Complex A
	Molecular Function	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation Protein N-linked Glycosylation Via Asparagine
Pathways	Asparagine N-linked glycosylation Maturation of spike protein Regulation of CDH1 posttranslational processing and trafficking to plasma membrane PD-L1(CD274) glycosylation and translocation to plasma membrane
GWAS	No GWAS studies recorded
Entrez ID	58505
HPRD ID	13120
Ensembl ID	ENSG00000198856
Uniprot IDs	A0A087WUD3 Q9NRP0
PDB IDs	6S7O 8B6L 8PN9
GO Terms Enriched among Interactors ?	Positive Regulation Of Cytosolic Calcium Ion Concentration Chemokine Receptor Activity Cytokine-mediated Signaling Pathway Trachea Gland Development Proteinase-activated Receptor Activity Positive Regulation Of Exocytosis Positive Regulation Of Glomerular Filtration Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium G Protein-coupled Receptor Activity Regulation Of Renin Secretion Into Blood Stream Positive Regulation Of Eosinophil Degranulation Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Protein Localization Positive Regulation Of Renin Secretion Into Blood Stream Chemokine-mediated Signaling Pathway CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Polyamine Transmembrane Transporter Activity Organelle Membrane Fusion Spermine Transport Extracellular Exosome Biogenesis Vesicle Fusion P-type Transmembrane Transporter Activity Spermine Transmembrane Transport Organelle Fusion ABC-type Polyamine Transporter Activity Box C/D Sno(s)RNA 3'-end Processing U6 2'-O-snRNA Methylation Death Receptor Agonist Activity Positive Regulation Of Protein Secretion Positive Regulation Of Killing Of Cells Of Another Organism Extracellular Vesicle Biogenesis P-type Ion Transporter Activity Regulation Of Autophagosome Size Membrane Fusion Positive Regulation Of SnRNA Transcription By RNA Polymerase II 7SK SnRNP Regulation Of Protein Localization To Nucleus Hair Follicle Placode Formation Salivary Gland Cavitation Mature Conventional Dendritic Cell Differentiation Thrombin-activated Receptor Activity Negative Regulation Of Lysosomal Protein Catabolic Process Cupric Ion Binding Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Cytotoxicity Regulation Of Exocytosis SnRNA Modification Glucose Import In Response To Insulin Stimulus Positive Regulation Of Toll-like Receptor 2 Signaling Pathway