NKX3-2

Gene Name		NK3 homeobox 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Transcription From RNA Polymerase II Promoter Determination Of Left/right Symmetry Pancreas Development Negative Regulation Of Chondrocyte Differentiation Middle Ear Morphogenesis Negative Regulation Of Apoptotic Process Spleen Development Organ Formation Skeletal System Morphogenesis Embryonic Skeletal System Development Intestinal Epithelial Cell Development
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: HDAC1 SMAD1 SMAD4
Entrez ID		579
HPRD ID		09075
Ensembl ID		ENSG00000109705
Uniprot IDs		P78367
PDB IDs
Enriched GO Terms of Interacting Partners?		Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta SMAD Protein Complex Assembly Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Embryonic Morphogenesis BMP Signaling Pathway Embryonic Pattern Specification Transcription From RNA Polymerase II Promoter Enzyme Linked Receptor Protein Signaling Pathway Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Negative Regulation Of Cell Death Mesonephros Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Formation Involved In Morphogenesis Epithelium Development Mesoderm Development Embryo Development Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Kidney Epithelium Development Positive Regulation Of Cell Morphogenesis Involved In Differentiation Transcription Initiation From RNA Polymerase II Promoter Gastrulation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Nephrogenic Mesenchyme Morphogenesis Regulation Of Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Skin Development DNA-templated Transcription, Initiation Positive Regulation Of Gene Expression Regulation Of Cell Death Positive Regulation Of Cellular Biosynthetic Process Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Tissue Development Cell Fate Commitment Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Cellular Response To Organic Substance Renal System Development Cellular Protein Complex Assembly Endocardial Cell Differentiation Primary MiRNA Processing Urogenital System Development
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