HES4

Description		hes family bHLH transcription factor 4
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Anterior/posterior Pattern Specification Cell Differentiation
Pathways
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549)
Interacting Genes		5 interacting genes: COPG2 LTN1 PCBD1 PCBD2 RGS3
Entrez ID		57801
HPRD ID		16273
Ensembl ID		ENSG00000188290
Uniprot IDs		D6REB3 E9PB28 Q9HCC6
PDB IDs
Enriched GO Terms of Interacting Partners?		4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Tetrahydrobiopterin Biosynthetic Process Tetrahydrobiopterin Metabolic Process Pteridine-containing Compound Biosynthetic Process Diol Metabolic Process Pteridine-containing Compound Metabolic Process Tyrosine Biosynthetic Process Phenylalanine 4-monooxygenase Activity Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Lyase Activity RQC Complex Alcohol Metabolic Process Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Ribosomal Large Subunit Binding COPI-coated Vesicle COPI Vesicle Coat Tyrosine Metabolic Process COPI-coated Vesicle Membrane Bounding Membrane Of Organelle Small Molecule Biosynthetic Process
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