EPG5

Name	ectopic P-granules 5 autophagy tethering factor
Structure
Interactors	2 interactors: ATF7IP CREBBP
GO Annotations	Cellular Component	Cytoplasm Lysosome Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	Mucosal Immune Response Ubiquitin-dependent Protein Catabolic Process Nucleotide Transport Autophagy Apoptotic Process Inflammatory Response Response To Unfolded Protein Endosome To Lysosome Transport Response To Virus Gene Expression Protein Catabolic Process Intracellular Receptor Signaling Pathway Endocytic Recycling Toll-like Receptor 9 Signaling Pathway Response To Type III Interferon Innate Immune Response Photoreceptor Cell Differentiation Homeostasis Of Number Of Cells Host-mediated Modulation Of Intestinal Microbiota Composition Homeostasis Of Number Of Retina Cells Neuron Apoptotic Process Defense Response To Virus Anatomical Structure Homeostasis Inclusion Body Assembly Autophagosome Maturation Maintenance Of Protein Complex Location Protein Aggregate Center Assembly Interferon-mediated Signaling Pathway Cellular Response To DsDNA
GWAS	Kawasaki disease ( 33692975 ) Sum of carotid plaque area ( 32469969 ) Sum of stenosis ( 32469969 )
Entrez ID	57724
HPRD ID	11157
Ensembl ID	ENSG00000152223
Uniprot IDs	A0A8Q3SIJ2 A0A8Q3SIU6 Q9BTI0 Q9HCE0
PDB IDs	7JHX
GO Terms Enriched among Interactors ?	Transcription Regulator Complex Histone H3K18 Acetyltransferase Activity Transcription Corepressor Activity N-terminal Peptidyl-lysine Acetylation Transcription Coregulator Activity Histone H3K27 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Nuclear Body MRF Binding Peptidyl-lysine Acetylation Negative Regulation Of Transcription By RNA Polymerase I Chromatin Remodeling N-terminal Protein Amino Acid Acetylation Acetyltransferase Activity Regulation Of Cellular Response To Heat Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Chromatin Organization Histone Acetyltransferase Complex Negative Regulation Of Transcription By RNA Polymerase II Protein K48-linked Deubiquitination Protein-lysine-acetyltransferase Activity Protein Acetylation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Acetyltransferase Activity DNA Methylation-dependent Constitutive Heterochromatin Formation Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Transcription By RNA Polymerase I Tau Protein Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryonic Digit Morphogenesis Negative Regulation Of RNA Metabolic Process Transcription Coactivator Binding Protein Destabilization Canonical NF-kappaB Signal Transduction Constitutive Heterochromatin Formation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Damaged DNA Binding P53 Binding Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Energy Homeostasis Positive Regulation Of DNA Recombination Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Double-strand Break Repair Via Homologous Recombination Cellular Response To UV Chromatin DNA Binding Regulation Of Smoothened Signaling Pathway Positive Regulation Of Double-strand Break Repair