MIER1

Description		MIER1 transcriptional regulator
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Transcription Repressor Complex Protein-containing Complex
	Molecular Function	Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of DNA-templated Transcription Positive Regulation Of Canonical NF-kappaB Signal Transduction
Pathways
Drugs
Diseases
GWAS		Allergic rhinitis ( 30013184) Appendicular lean mass ( 33097823) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Lymphocyte percentage of white cells ( 27863252) Monocyte count ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		7 interacting genes: APP CREBBP H3-4 HDAC1 LIG1 SP1 TMEM171
Entrez ID		57708
HPRD ID		11362
Ensembl ID		ENSG00000198160
Uniprot IDs		Q8N108
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin Remodeling Positive Regulation Of Amyloid Precursor Protein Catabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Host-mediated Perturbation Of Viral Transcription Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Chromatin Organization Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Apoptotic Signaling Pathway Embryonic Digit Morphogenesis P53 Binding Rhythmic Process Host-mediated Perturbation Of Viral Process Transcription Repressor Complex Heterochromatin Okazaki Fragment Processing Involved In Mitotic DNA Replication Positive Regulation Of Hydrogen Sulfide Biosynthetic Process Cellular Response To Wortmannin DNA Binding Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Chromatin Binding Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Transcription By RNA Polymerase II Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Histone H3K27 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Krueppel-associated Box Domain Binding Histone Deacetylase Binding Protein Lysine Delactylase Activity Fungiform Papilla Formation Modulation Of Process Of Another Organism Host-mediated Perturbation Of Symbiont Process DNA Ligase (ATP) Activity Lagging Strand Elongation DNA Replication, Okazaki Fragment Processing DNA Ligase Activity
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