LRRN1

Description		leucine rich repeat neuronal 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Protein Binding Signaling Receptor Activity
	Biological Process	Positive Regulation Of Synapse Assembly
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Age at first sexual intercourse ( 34211149) Callous-unemotional behaviour ( 23874384) Fractures (paediatric) ( 32742401) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Knee osteoarthritis ( 27696742) Metabolite levels ( 23823483) Refractive error ( 32231278) Restless legs syndrome ( 29029846) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		2 interacting genes: PDCD6IP TRAF1
Entrez ID		57633
HPRD ID		14320
Ensembl ID		ENSG00000175928
Uniprot IDs		A8K6Q2 Q6UXK5
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Vesicle Biogenesis Extracellular Exosome Biogenesis Positive Regulation Of Extracellular Exosome Assembly Proteinase Activated Receptor Binding Actomyosin Contractile Ring Assembly Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Extracellular Exosome Assembly Thioesterase Binding Actomyosin Maintenance Of Cell Polarity Positive Regulation Of Exosomal Secretion Cell Death Tumor Necrosis Factor Receptor Binding Programmed Cell Death Apoptotic Process Cortical Actin Cytoskeleton Organization Mitotic Cytokinetic Process Flemming Body Multivesicular Body Organization Viral Budding Regulation Of Exosomal Secretion Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Multivesicular Body Assembly Midbody Abscission Regulation Of Spindle Assembly Endoplasmic Reticulum Exit Site Protein-containing Complex Assembly Regulation Of Mitotic Spindle Organization Cortical Cytoskeleton Organization Immunological Synapse Bicellular Tight Junction Assembly Cytokinetic Process Mitotic Metaphase Chromosome Alignment Regulation Of Centrosome Duplication Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Tight Junction Assembly Establishment Or Maintenance Of Apical/basal Cell Polarity Protein-containing Complex Organization Tight Junction Organization Metaphase Chromosome Alignment Regulation Of Centrosome Cycle Tumor Necrosis Factor-mediated Signaling Pathway Mitotic Cytokinesis Regulation Of Membrane Permeability Signaling Adaptor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Chromosome Localization Calcium-dependent Protein Binding
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