ARID1B

Gene Name		AT rich interactive domain 1B (SWI1-like)
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm SWI/SNF Complex NBAF Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding
	Biological Process	Transcription, DNA-templated Nervous System Development Chromatin-mediated Maintenance Of Transcription
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS		Alzheimer's disease biomarkers ( 23419831) Pancreatic cancer ( 22158540) Uric acid levels ( 21294900)
Protein-protein Interactions		5 interactors: CUL2 HIST2H2BE SMAD9 SMARCA2 SMARCA4
Entrez ID		57492
HPRD ID		10660
Ensembl ID		ENSG00000049618
Uniprot IDs		Q8NFD5
PDB IDs		2CXY 2EH9
Enriched GO Terms of Interacting Partners?		Aortic Smooth Muscle Cell Differentiation Vascular Smooth Muscle Cell Differentiation Smooth Muscle Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Nucleosome Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Chromatin Assembly Or Disassembly Negative Regulation Of Cell Growth Hindbrain Development Chromatin Remodeling Chromosome Organization DNA Methylation On Cytosine Within A CG Sequence Negative Regulation Of Growth Definitive Erythrocyte Differentiation Response To Hypoxia Glial Cell Fate Determination Methylation-dependent Chromatin Silencing Mullerian Duct Regression Positive Regulation Of Transcription, DNA-templated Muscle Cell Differentiation Regulation Of Cell Growth Positive Regulation By Host Of Viral Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression DNA Methylation On Cytosine Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Androgen Receptor Signaling Pathway Nucleosome Disassembly Blastocyst Hatching Negative Regulation Of Cell Cycle Heart Trabecula Formation Innate Immune Response In Mucosa Anatomical Structure Regression Lens Fiber Cell Development Muscle Structure Development Regulation Of Androgen Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Glial Cell Fate Commitment Regulation Of Nucleic Acid-templated Transcription Vasculature Development Regulation Of RNA Biosynthetic Process Definitive Hemopoiesis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of RNA Metabolic Process Antibacterial Humoral Response Heart Trabecula Morphogenesis Antimicrobial Humoral Response Chromatin Modification Blastocyst Growth
Tagcloud ?		arid2 baf bcl11a bcl11b brd9 calu catalogue constructs cosmic deposited driver establishment existed hairpin knocked mswi mutated ones pearson psuper ranking reporters shrna slippage smarca4 snf sublines swi typing