ATP10A

Description		ATPase phospholipid transporting 10A (putative)
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Phospholipid-translocating ATPase Complex
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Binding ATP Binding ATP Hydrolysis Activity Metal Ion Binding Phosphatidylcholine Floppase Activity ATPase-coupled Intramembrane Lipid Transporter Activity Phosphatidylcholine Flippase Activity Glycosylceramide Flippase Activity
	Biological Process	Lipid Transport Regulation Of Cell Shape Phospholipid Transport Monoatomic Ion Transmembrane Transport Phospholipid Translocation Positive Regulation Of Membrane Tubulation
Pathways		Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Cutaneous melanoma or hair colour ( 32341527) Diastolic blood pressure ( 30224653) HOMA-B (corrected for HOMA-IR) ( 30369944) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Insulin resistance/response ( 21901158) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Phenylephrine infusion rate during anesthesia ( 31455332) Refractive error ( 32231278)
Novel Interacting Genes		1 novel interacting genes: FOXJ1
Interacting Genes		1 interacting genes: CLK1
Entrez ID		57194
HPRD ID		05790
Ensembl ID		ENSG00000206190
Uniprot IDs		O60312
PDB IDs
Enriched GO Terms of Interacting Partners?		Central Tolerance Induction Positive Regulation Of Lung Ciliated Cell Differentiation Glomerular Parietal Epithelial Cell Development Positive Regulation Of B Cell Tolerance Induction Positive Regulation Of Central B Cell Tolerance Induction Negative Regulation Of Germinal Center Formation Metanephric Part Of Ureteric Bud Development Ciliary Basal Body Organization Regulation Of Germinal Center Formation Negative Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Tolerance Induction Lung Epithelium Development Left/right Pattern Formation Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Tolerance Induction Regulation Of Tolerance Induction Establishment Of Apical/basal Cell Polarity Establishment Of Monopolar Cell Polarity Regulation Of T Cell Differentiation In Thymus Establishment Or Maintenance Of Monopolar Cell Polarity Protein Serine/threonine/tyrosine Kinase Activity Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Negative Regulation Of B Cell Activation Non-membrane Spanning Protein Tyrosine Kinase Activity Motile Cilium Assembly Negative Regulation Of Interleukin-6 Production Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Humoral Immune Response Axoneme Assembly Negative Regulation Of T Cell Differentiation Negative Regulation Of Lymphocyte Differentiation Positive Regulation Of Epithelial Cell Differentiation Negative Regulation Of Adaptive Immune Response Negative Regulation Of T Cell Proliferation Negative Regulation Of Lymphocyte Proliferation Determination Of Bilateral Symmetry Negative Regulation Of Mononuclear Cell Proliferation Microtubule Organizing Center Organization Establishment Of Cell Polarity Determination Of Left/right Symmetry Microtubule Bundle Formation Negative Regulation Of Leukocyte Proliferation Regulation Of Non-canonical NF-kappaB Signal Transduction
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