CASS4

Description		Cas scaffold protein family member 4
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Anchoring Junction
	Molecular Function	Protein Binding Protein Tyrosine Kinase Binding
	Biological Process	Cell Adhesion Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cell Migration Positive Regulation Of Cell Migration Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 24162737 30617256) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Cognitive decline (age-related) ( 28078323) Family history of Alzheimer's disease ( 30617256) Platelet count ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Refractive astigmatism ( 25367360)
Novel Interacting Genes		1 novel interacting genes: RAE1
Interacting Genes		5 interacting genes: ANKS1B CDC42EP2 FHL3 HSF2BP ZYX
Entrez ID		57091
HPRD ID		09842
Ensembl ID		ENSG00000087589
Uniprot IDs		B4DII4 Q9NQ75
PDB IDs		2CRE
Enriched GO Terms of Interacting Partners?		Organelle Organization Actin Filament-based Process Actin Cytoskeleton Organization Stress Fiber Phagocytic Vesicle Cellular Response To Type II Interferon Response To Type II Interferon Opioid Peptide Activity Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Female Meiosis I
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