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PRSS8

Name serine protease 8
Structure PDB 3DFJ
Novel Interactors 1 novel interactors: HNRNPLL
Interactors 2 interactors: ATF7IP SLC13A1
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Plasma Membrane
  • Membrane
  • Extracellular Exosome
Molecular Function
  • Serine-type Endopeptidase Activity
  • Protein Binding
  • Peptidase Activity
  • Serine-type Peptidase Activity
  • Hydrolase Activity
Biological Process
  • Proteolysis
  • Positive Regulation Of Sodium Ion Transport
Pathways
  • Formation of the cornified envelope
Drugs
  • 1-[4-(hydroxymethyl)phenyl]guanidine
GWAS
  • Bipolar disorder ( 31043756 )
  • Bipolar I disorder ( 31043756 )
Entrez ID 5652
HPRD ID 02895
Ensembl ID ENSG00000052344
Uniprot IDs Q16651
PDB IDs 3DFJ 3DFL 3E0N 3E0P 3E16 3E1X 3FVF 3GYL 3GYM
GO Terms Enriched among Interactors ?
  • Sodium:sulfate Symporter Activity
  • Monoatomic Anion:sodium Symporter Activity
  • Secondary Active Sulfate Transmembrane Transporter Activity

© Madhavi K. Ganapathiraju 2012-2026