MESP1

Description		mesoderm posterior bHLH transcription factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Mesoderm Formation Heart Looping Heart Morphogenesis Heart Induction Secondary Heart Field Specification Embryonic Heart Tube Morphogenesis Cardiac Atrium Formation Cardiac Ventricle Formation Sinus Venosus Morphogenesis Growth Involved In Heart Morphogenesis Cardioblast Anterior-lateral Migration Cardioblast Migration Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Gastrulation Mesodermal Cell Migration Gene Expression Neurogenesis Signal Transduction Involved In Regulation Of Gene Expression Somite Rostral/caudal Axis Specification Negative Regulation Of Mesodermal Cell Fate Specification Negative Regulation Of Endodermal Cell Fate Specification Endothelial Cell Differentiation Positive Regulation Of Notch Signaling Pathway Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Lateral Mesoderm Development Positive Regulation Of Striated Muscle Cell Differentiation Cardiac Muscle Cell Differentiation Cardiac Cell Fate Determination Sinoatrial Node Cell Differentiation Cardiac Vascular Smooth Muscle Cell Differentiation Cardioblast Migration To The Midline Involved In Heart Field Formation Positive Regulation Of Hepatocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Cardiogenesis
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		1 interacting genes: ZIC3
Entrez ID		55897
HPRD ID		10070
Ensembl ID		ENSG00000166823
Uniprot IDs		Q9BRJ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Neural Plate Development Central Nervous System Segmentation Determination Of Left/right Asymmetry In Nervous System Axial Mesoderm Development Germ-line Stem Cell Population Maintenance Determination Of Pancreatic Left/right Asymmetry Determination Of Liver Left/right Asymmetry Determination Of Digestive Tract Left/right Asymmetry Paraxial Mesoderm Development Outer Ear Morphogenesis Primitive Streak Formation Left/right Axis Specification Atrial Cardiac Muscle Tissue Development Left/right Pattern Formation Cranial Skeletal System Development Face Development Olfactory Bulb Development Cardiac Muscle Tissue Development MRNA Transcription MRNA Transcription By RNA Polymerase II Gastrulation Mesenchyme Development Segmentation Embryonic Pattern Specification Mesoderm Development Heart Looping Forebrain Development Hippocampus Development Embryonic Heart Tube Morphogenesis Axis Specification Smoothened Signaling Pathway Determination Of Bilateral Symmetry Determination Of Left/right Symmetry Limb Morphogenesis Epithelial Tube Morphogenesis Lung Development Stem Cell Differentiation Stem Cell Population Maintenance Maintenance Of Cell Number Striated Muscle Tissue Development Central Nervous System Development Muscle Tissue Development Anterior/posterior Pattern Specification Skeletal System Development Epithelium Development Heart Development Regionalization Gene Expression Transcription Coactivator Activity Transcription By RNA Polymerase II
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